Tushar Chandra MD, Presenter: Nothing to Disclose

Teresa Gross Kelly MD, Abstract Co-Author: Nothing to Disclose

Saurabh Guleria MD, Abstract Co-Author: Nothing to Disclose

Suyash Mohan MD, Abstract Co-Author: Nothing to Disclose

Hervey D. Segall MD, Abstract Co-Author: Nothing to Disclose

Mohit Maheshwari MD, Abstract Co-Author: Nothing to Disclose

The aim of this exhibit is to provide a succinct review of the spectrum of various metabolism disorders that affect the CNS in pediatric age group. We will elucidate a pattern based approach and describe specific pointers to formulate a diagnosis .

1. Relevant anatomy and imaging pearls 2. Clinical considerations: diagnostic clues 2. Metabolic conditions involving the gray matter 3. Metabolic conditions involving the white matter 4. Metabolic conditions involving gray and matter 5. Imaging approach and diagnostic algorithm  

A myriad of metabolic conditions involve the brain in pediatric age group. These include abnormalities of lipid and glycogen storage, mitochondrial disorders, urea cycle disorders and some other rare enzyme deficiencies. Proper diagnosis of these conditions can be very challenging, even for the astute radiologist. Magnetic resonance imaging including spectroscopy is a powerful tool in the study of normal and abnormal brain structure, function and biochemistry. This exhibit attempts to simplify the diagnostic approach to these disorders with a pattern based approach to formulate a differential diagnosis and pointers to a specific diagnosis, whenever possible.  

Chandra, T, Kelly, T, Guleria, S, Mohan, S, Segall, H, Maheshwari, M, Demystifying Pediatric Neurometabolic Disorders.  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13024318.html