Ulysses Santos Torres MD, Abstract Co-Author: Nothing to Disclose

Eduardo Portela De Oliveira, Presenter: Nothing to Disclose

Fernanda Del Campo Braojos Braga MD, Abstract Co-Author: Nothing to Disclose

Horacio Jose Ramalho, Abstract Co-Author: Nothing to Disclose

Antonio Soares Souza MD, Abstract Co-Author: Nothing to Disclose

Jose Roberto Lopes Ferraz-Filho, Abstract Co-Author: Nothing to Disclose

This education exhibit aims to: 1) Discuss the spectrum of neurological complications related to immunosuppression in the setting of solid organ transplantation (SOT). 2) Categorize these complications in major groups according their clinical and radiological manifestations, facilitating the diagnostic approach by radiologists. 3) Illustrate the main neuroimaging findings of confirmed cases of immunosuppression-related complications occurring in SOT recipients.

This exhibit will address the spectrum of immunosuppression-related neurological complications after SOT (mainly kidney and liver transplants) in a case-based format. Representative cases will include calcineurin-inhibitors’ neurotoxicity, neurotoxoplasmosis, neurocryptococcosis, cerebral aspergillosis, cerebral pyogenic abscesses, encephalitis due to Chagas’ disease reactivation, cerebral lymphomas, among others.

Immunosuppression has improved graft survival in SOT recipients, but it leaves the patient susceptible to a gamut of CNS complications occurring within a few days to several years after the procedure. Neuroimaging has a pivotal role in characterizing these complications. After reviewing this exhibit, radiologists should be able to recognize the main correspondent imaging findings in this setting and to formulate appropriate differential diagnoses.

Torres, U, De Oliveira, E, Braojos Braga, F, Ramalho, H, Souza, A, Ferraz-Filho, J, Neuroimaging of Immunosuppression-related Complications in Solid Organ Transplant Recipients: A Pictorial Review.  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13023948.html