The purpose of the exhibit is
1. To review the pathophysiology of Immune Reconstitution Inflammatory Syndrome (IRIS)
2. To discuss the clinical manifestations of IRIS
3. To illustrate using a multimodality approach the radiological manifestations of IRIS
4. To discuss the potential role of the Radiologist in the management of IRIS
Pathophysiology of Immune Reconstitution Inflammatory Syndrome (IRIS)
Clinical manifestations of Immune Reconstitution Inflammatory Syndrome (IRIS)
Review of imaging findings of Immmune Reconsitution Inflammatory Syndrome:
with Tuberculosis
with Progressive Multifocal Leucoencephalopathy
with Kaposi Sarcoma
with others
Role of radiology in the management of Immune Reconsitution Inflammatory Syndrome
The major teaching points of this exhibit are:
1. In the era of Highly Active Antiretroviral Antiretroviral Therapy the understanding and recognision of Immune Reconstitution Inflammatory Syndrome (IRIS) is becoming increasingly important.
2. Radiological features may manifest as "unmasking" of opportunistic infections,paradoxical worsening of an existing infection or condition or may be atypical.
3. There is a role for the Radiologist in the management of IRIS primarily in image guided drainage and biopsy.
Symeonidou, C,
Abdullah, S,
Webster, D,
Immune Reconstitution Inflammatory Syndrome (IRIS): A Radiologist's Perspective. Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL.
http://archive.rsna.org/2013/13020661.html
