Gunhild Erstad Aandal MD, Presenter: Research funded, Siemens AG

Ronald David Novak PhD, Abstract Co-Author: Nothing to Disclose

Salim E. Abboud MD, Abstract Co-Author: Nothing to Disclose

Christos Kosmas MD, Abstract Co-Author: Nothing to Disclose

Mark Richard Robbin MD, Abstract Co-Author: Nothing to Disclose

Two of the most common bone biopsy systems used in CT guided bone biopsy procedures are Laurane Bone Biopsy Kit and Bonopty Bone Biopsy Kit. In our department, we changed from using the Bonopty system to using the Laurane system in October 2008. The Laurane system was considered by our MSK radiologists to be both technically easier to use and appeared to generate larger osseous sample cores. The purpose of this study was to compare the two systems to determine which provided the best accuracy compared to the final clinical diagnosis.

This retrospective study was a review of bone biopsies performed in which the Laurane Biopsy Kit was used in 88 consecutive patients and the Bonopty Biopsy Kit was used in 93 consecutive patients. The Laurane cohort consisted of 58% females and 42% males with a mean age of 60.8 years (median = 62.4 years). The Bonopty cohort consisted of 64% females and 36% males with a mean age of 62.9 years (median = 64.4 years). All biopsies were core samples from suspected neoplasms. Spine biopsies for evaluation of discitis/osteomyelitis were excluded from this study. Differences in proportions of accurate diagnoses were measured using the Chi-Square differences in proportions test. P-values less than 0.05 were considered to be significant.

A comparison of diagnostic accuracy derived from Laurane and Bonopty samples was not found to be statistically significantly different, 87.5%(Laurane) vs 79.6%(Bonopty), p=0.212. Retrospective review of pathology reports showed there was no significant difference in sample quality provided to pathology when the two biopsy systems were compared (p=0.455). Lesion location and prevalence of malignant versus benign disease were also not significantly different between the two patient cohorts.

The results of this pilot study suggest that there is no statistically significant difference in diagnostic accuracy of core samples derived from osseous lesions using either of the bone biopsy systems. Other factors (cost, availability, convenience, etc.) may be considered in the determination of which bone biopsy system to be used.

A comparison of two commercially available bone biopsy systems did not demonstrate significantly different diagnostic accuracy, exempting accuracy as a criterion for either purchase and/or utilization

Aandal, G, Novak, R, Abboud, S, Kosmas, C, Robbin, M, A Comparison of the Diagnostic Accuracy between the Use of Two Different Bone Biopsy Systems.  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13020531.html