Dalia Salah El Din El Mesidy MBBCh, MSc, Presenter: Nothing to Disclose

Rasha Mohamed Kamal MD, Abstract Co-Author: Nothing to Disclose

Sahar Mansour MD, Abstract Co-Author: Nothing to Disclose

Ahmed Hussein Khalil MSc, MD, Abstract Co-Author: Nothing to Disclose

To assess the additional role of DBT and MRI in comparison to conventional DM in the characterization of different breast lesions and to evaluate their impact on diagnosis and consequent management.

55 patients, having 60 breast lesions were referred from the Surgery clinic to the Radiology Department to be assessed by DM, DBT and MRI. An informed written consent to participate in the study was obtained from all patients. Breast US was performed for all cases.Mammography images were acquired using the "combo mode", a feature that acquires both a DM and a DBT scan in the same compression. MRI was performed using a 1 T system. Each lesion was assigned a blinded BIRADS score for each modality (DM, DBT and MRI) individually by different readers blinded to each other results. BIRADS scores of 1-3 were considered benign, and BIRADS scores of 4 and 5, were considered malignant. The resultant BIRADS scores for each modality were correlated with reports of pathology specimens.

The sensitivity for DM was 87% and those of  DBTand MRI were equivalent to 93.75%. The specificity for DM was 50%,that for DBT was 84.1% and that of MRI was 86.36%.The PPV of DM was 38.89%,that of DBT was 68.18% and that of MRI was 71.43%, whereas the NPV of DM was 91.7% and that of each of DBT and MRI was 97.4%.The efficacy of DM was 60%,that of DBT was 86.7% and that of MRI was 88.3%. Association between DM,DBT and MRI finding results and the final diagnoses revealed highly significant correlation, having p-values of 0.009 for DM and 0.001 for each of DBT and MRI. Association between the results of DM and those of DBT showed that DBT had a statistically significant higher diagnostic value for diagnosing breast lesions than DM, having a p-value of 0.005.However,the association between the results of DM and those of MRI showed that there is no statistically significant difference between DM and MRI, with a p-value of 0.422.The association between the results of DBT and those of MRI showed that there is a statistically significant difference between DBT and MRI for diagnosing breast lesions, with a p-value of 0.043.

Both MRI and DBT showed better performance than did DM. Both can add a lot to the information gained for better diagnosis and prompt management of breast lesions.

Both DBT and MRI are better than DM in detecting or excluding breast cancer, specially in cases with dense breasts.

El Mesidy, D, Kamal, R, Mansour, S, Khalil, A, Digital Breast Tomosynthesis (DBT) and Breast Magnetic Resonance Imaging (MRI): Additional Roles as Compared to Conventional Digital Mammography (DM) in Assessment of Breast Disease.  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13015707.html