Rosa M. Lorente-Ramos MD, PhD, Presenter: Nothing to Disclose

Javier Azpeitia Arman MD, Abstract Co-Author: Nothing to Disclose

Eva Cueva Perez, Abstract Co-Author: Nothing to Disclose

Isabel Casado Farinas, Abstract Co-Author: Nothing to Disclose

Teresa Rivera Garcia, Abstract Co-Author: Nothing to Disclose

Miguel Angel Lara Alvarez, Abstract Co-Author: Nothing to Disclose

To review imaging findings in advanced breast cancer after neoadjuvant chemotherapy with correlation with pathological changes occurring during treatment. To analyse and illustrate the appropriate description and reporting of the differente types of radiological response to neoadjuvant therapy, including residual tumor features and complete remission.

The imaging findings in 62 patients with advanced breast cancer undergoing neoadjuvant chemotherapy (NAC) were reviewed and compared with responses after treatment and pathological findings at surgery. Mammograms, US and MR, dynamic contrast-enhanced and diffusion weighted imaging (DWI), were performed in all the patients before and after NAC. We describe and illustrate a schematic reporting system including a description of the residual lesion with comparison with the pretreatment tumor: - morphologic type of response: absence of lesion (complete response), mass shrinkage, fragmentation (scattered foci) - tumour size (longest diameter and volume) - tumour signal intensity on MR T2-weighted images - peak signal enhancement ratio on dynamic contrast-enhanced MR - ADC ratio - response in lymph nodes

Imaging features correlate with pathologic findings after surgery. Accurate description and reporting of the differente types of radiological response helps in tumor evaluation.

Lorente-Ramos, R, Azpeitia Arman, J, Cueva Perez, E, Casado Farinas, I, Rivera Garcia, T, Lara Alvarez, M, Do We Describe the Response of Breast Cancer to Neoadjuvant Chemotherapy Accurately? A Systematic Approach to Reporting.  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13011823.html