Hye Sun Hwang, Presenter: Nothing to Disclose

Myung Jin Chung MD, Abstract Co-Author: Patent agreement, General Electric Company Patent agreement, Samsung Electronics Co Ltd

Hyun-Hwa Oh PhD, Abstract Co-Author: Employee, Samsung Electronics Co Ltd

Seoyoung Choi PhD, Abstract Co-Author: Employee, Samsung Electronics Co Ltd

Kangeui Lee PhD, Abstract Co-Author: Employee, Samsung Electronics Co Ltds

Younghun Sung PhD, Abstract Co-Author: Employee, Samsung Electronics Co Ltd

Kyung Soo Lee MD, PhD, Abstract Co-Author: Nothing to Disclose

To compare the capability of lung nodule detection and characterization between Dual-energy radiography with color-representation (DCR) and conventional gray scale chest radiography (GSR)

A total of 130 paired chest radiographs (DCR and GSR) taken from 14 normal subjects and 51 patients with pulmonary nodules were evaluated. The 51 patients had 45 non-calcified and 21 calcified nodules. DCR was obtained by adding color space within material-decomposed data (applying blue color for high attenuating component and red color for low attenuating component) and by compounding the manipulated data to one color image. Three radiologists marked suggested nodules on radiographic images and assessed the confidence of lesion presence and probability of nodule calcification by using a nine-point rating scale. The jackknife active free-response receiver operating characteristics (JAFROC) analysis was used to evaluate lesion detectability, and multi-reader multi-case receiver operating characteristics (MRMC ROC) analysis was used for the evaluation of the accuracy of nodule calcification prediction.

Figures of merit (FOM) from JAFROC were 0.806 for DCR and 0.811 for GSR, respectively; thus, nodule detectability was not significantly different between DCR and GSR (P = .93). Areas under curve (AUC) from MRMC ROC were 0.927 for DCR and 0.781 for GSR, respectively; thus, performance of DCR in predicting lung nodule calcification was significantly better than that of GSR (P = .04).

DCR shows similar performance in lung nodule detection compared with GSR. However, DCR does provide a significant benefit in predicting the presence of nodule calcification.

DCR has additional value for lung nodule characterization to conventional gray scale radiography.

Hwang, H, Chung, M, Oh, H, Choi, S, Lee, K, Sung, Y, Lee, K, Color Radiography in Lung Nodule Detection and Characterization: Comparison with Conventional Gray Scale Radiography.  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13010923.html