Gabriel Fernando Daza Cajas MD, Presenter: Nothing to Disclose

Jhon Jairo Echeverri MD, Abstract Co-Author: Nothing to Disclose

Classification and review of the acute and chronic abnormalities of the musculoskeletal system in hemophilic patients. Pathophysiology of the complications in this group of patients To identify findings in plain radiography, CT and MRI as part of the management protocol of musculoskeletal injuries.

Retrospective case series based on the cohort of patients with hemophilia in a referral center. We describe factor VIII deficiency, its etiology, global pathophysiology, and overall the most common and expected manifestations on the musculoskeletal system in patients with hemophilia. Description of the most prevalent radiological findings in patients who are part of an cohort of 500 individuals. Multimodal approach with surgical-pathologic correlation.

Approximately 150 events of documented pathology in the musculoskeletal system of the cohort are described. Approximation flowcharts are established for the diagnosis of pathology prevalent in patients with this disease: - Traumatic Injuries - Injuries with arthritic consequences - Pseudo tumor-like lesions - Intra Abdominal Injury

Hemophilia is an entity which, under controlled circumstances, allows an adequate quality of life and an acceptable survival rate. However, unless there is an accurate and early diagnosis, as well as intervention by a multidisciplinary team of specialists in hematological disease which could prevent or reduce complications and sequelae attributable to bleeding in the musculoskeletal system, everyday circumstances can generate unexpected complications affecting the musculoskeletal system significantly.

This paper is clinically useful for providers specialized in the management of patients with coagulation factor deficiency. These include orthopedists, hematologists and radiologists.

Daza Cajas, G, Echeverri, J, "When Blood Corrodes" Musculoskeletal System Manifestations of Hemophilia A Multimodal Approach in a Cohort.  Radiological Society of North America 2013 Scientific Assembly and Annual Meeting, December 1 - December 6, 2013 ,Chicago IL. http://archive.rsna.org/2013/13010187.html