RSNA 2012 

Abstract Archives of the RSNA, 2012


LL-PHS-WE2D

Effect of Adaptive Statistical Iterative Reconstruction Technique on CT Imaging Measurement of Emphysema

Scientific Informal (Poster) Presentations

Presented on November 28, 2012
Presented as part of LL-PHS-WEPM: Physics Afternoon CME Posters

Participants

Jian-Xing Qiu MD, Presenter: Nothing to Disclose
Xiaoying Wang MD, Abstract Co-Author: Nothing to Disclose
Xiaochao Guo, Abstract Co-Author: Nothing to Disclose
Rui Wang PhD, Abstract Co-Author: Nothing to Disclose

PURPOSE

To assess the effect of adaptive statistical iterative reconstruction(ASiR) technique on quantitative measurement derived from computed tomography(CT) lung images of patients with emphysema.

METHOD AND MATERIALS

Fifteen patients(10 men and 5 women; range 62-86ys) clinically diagnosed as COPD, underwent a thoracic CT imaging protocol using GE Discovery CT750HD. Institutional review board approval and written informed consent were obtained before CT scanning. CT image raw data sets were reconstructed with filtered back projection(FBP) and ASiR-FBP composites at 10%, 30%, 50%, 70%, 90%. All images were reconstructed with a standard algorithm. Density mask(RA-950) and volume measurements from different ASiR-FBP composites were compared with FBP reconstruction. K related samples test (Friedman Type) was used to analysis the variance of density mask and volume measurements from FBP and different ASiR-FBP composites reconstruction.

RESULTS

Comparison with FBP, reconstruction with ASiR compsites at 10%, 30%, 50%, 70%, 90% did not yielded effect on the total lung volume measurements(P=0.057), but underestimated emphysema %(RA-950)(P<0.001) and emphysema volume(P<0.001). ASiR 90% yield an average shift of -15.1% in emphysema % and -15.0% in emphysema volume.

CONCLUSION

CT image raw data reconstruction with ASiR may effect density mask results, but not effect total lung volume.

CLINICAL RELEVANCE/APPLICATION

CT image raw data sets;were usually reconstructed with ASiR;to reduce noise in low radiation dose scanning,but ARiR technique may underestimate emphysema % and emphysema volume.

Cite This Abstract

Qiu, J, Wang, X, Guo, X, Wang, R, Effect of Adaptive Statistical Iterative Reconstruction Technique on CT Imaging Measurement of Emphysema.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12043873.html