Antoine Guillonnet PhD, Abstract Co-Author: Nothing to Disclose

Jerome Hodel, Presenter: Nothing to Disclose

Mathieu Henri Rodallec MD, Abstract Co-Author: Nothing to Disclose

Raphael BLANC MD, Abstract Co-Author: Nothing to Disclose

Sophie Gerber, Abstract Co-Author: Nothing to Disclose

Denis Trystram MD, Abstract Co-Author: Nothing to Disclose

Silvia Pistocchi, Abstract Co-Author: Nothing to Disclose

Catherine Oppenheim MD, PhD, Abstract Co-Author: Nothing to Disclose

Jean-Francois Meder MD, PhD, Abstract Co-Author: Nothing to Disclose

Jean-Pierre Pruvo MD, PhD, Abstract Co-Author: Nothing to Disclose

Xavier Leclerc MD, PhD, Abstract Co-Author: Nothing to Disclose

Marc Zins MD, Abstract Co-Author: Nothing to Disclose

To describe the technical aspects of the ASL sequence To understand the advantages of using 3D Fast Spin Echo (FSE) ASL To review clinical applications of 3D FSE ASL in the field of vascular imaging  

1) Technical aspects and post processing techniques 2) Advantages of using 3D FSE ASL 3) Pictorial review: perfusion patterns in stroke and brain vascular malformations (BVM) 4) Pitfalls and mimics 5) Take home messages  

ASL is a non contrast-perfusion technique that uses the magnetic labeling of the arterial water. Several parameters such as Post Label Delay time may affect image quality. ASL is improved at 3T due to the higher signal to noise ratio and longer T1 of blood. 3D ASL allows for both mutliplanar reformations and fusion with others sequences such as TOF or SWI. FSE imaging improves diagnosis accuracy in patients with aneurysm coils or blood products thanks to reduced susceptibility artifacts. ASL is very sensitive to a wide range of pathological vascular states such as hyperperfusion or slow flowing blood. In patients with stroke, ASL provides information about luxury perfusion, collateral routes or penumbra. ASL improves the detection of venous drainage in patients with small BVM. Steal phenomenon or arterial transit artifact may impair CBF quantification but are both useful markers of pathology.  

Guillonnet, A, Hodel, J, Rodallec, M, BLANC, R, Gerber, S, Trystram, D, Pistocchi, S, Oppenheim, C, Meder, J, Pruvo, J, Leclerc, X, Zins, M, A New Trend in Vascular Imaging: The Arterial Spin Labeling (ASL) Sequence.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12036108.html