Hong Chen MD, Presenter: Nothing to Disclose

Xiaoming Wang MD, Abstract Co-Author: Nothing to Disclose

The aim of this study is to evaluate the MRI patterns of brain injury after neonatal hypoglycemia .

We retrospectively reviewed the imaging database of 30 consecutive patients who were admitted to our hospital from 2006 to 2012 ,All the patients with neonatal hypoglycemia and brain Injury and without evident of hypoxic-ischemic encephalopathy .Hypoglycemia was defined as the condition in which the whole blood glucose concentration was blow 2.6mmol/l.

The predominant patterns of brain injury were as follows:1.Parieto-occipital lobe injury, most patients showed a predominance of abnormalities in the parieto-occipital lobes.Bilateral perieto-occipital cortex and subcortical white matter injury occur in 76.7% of all the infants (n=23); 10% infant had bilateral occipital cortex and subcortical white matter injury (n=3) ,while 3 infant with unilateral occipital lobe damage. 2. Corpus callosum lesions,Corpus callosum abnormalities occurred in 70% of the infants （n=21）,all including the splenium of the corpus callosum . 6 of them associated with the genu of the corpus callosum injury and 5 With the body of corpus callosum abnormalities 3.Frontal lobe injury , frontal injury abnormal occur in 36.7% of the infant (n=11). 4.Others, including the posterior limb of the internal capsule lesions (n=2),The basal ganglia(n=2), thalamic lesions(n=2) and focal periventricular white matter injury (n=6).All of lesions mentioned above showed restricted water diffusion on DWI.

A patters of bilateral perieto-occipital cortex and subcortical white matter injury associated the splenium of the corpus callosum lesions are most frequently seen in neonatal hypoglycemia .and MRI is helpful in the early detection and evaluation of hypoglycemic brain injury of neonates．  

To evaluate the MRI patterns of brain injury after neonatal hypoglycemia .And the patterns idetified on MRI might be valueable in the early detection and evaluation of hypoglycemic brain

Chen, H, Wang, X, MRI Findings of Neonatal Hypoglycemia Brain Injury.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12035170.html