Rakhee Kisan Sanzgiri MD, Presenter: Nothing to Disclose

Matthew W. Wilson MD, Abstract Co-Author: Nothing to Disclose

M. Beth McCarville MD, Abstract Co-Author: Nothing to Disclose

Kathleen J. Helton MD, Abstract Co-Author: Nothing to Disclose

 Intraocular medulloepithelioma is a rare childhood unilateral tumor arising from the non-pigmented ciliary epithelium. This  tumor mimics the clinical presentation of other common childhood intraocular tumors and is therefore often misdiagnosed as a retinoblastoma. Imaging characteristics of this tumor are not well known. We discuss the US and MRI based diagnostic features of this tumor that help in differentiating it from the more common retinoblastoma.

After IRB approval, retrospective review of data of 4 young males (2-9 years of age) with histological diagnosis of medulloepithelioma was performed. • We will describe the clinical presentation of this tumor. • Through visual images, we will describe the unique and variable imaging findings using advanced orbital MRI and US techniques and features that correlate with the need for metastatic work-up. • We will describe the unique pathological characteristics of this tumor and features that correlate with the need for metastatic work-up.  

Though medulloepithelioma is a rare childhood tumor, it can be readily distinguished from the more common retinoblastoma on radiological imaging, despite similar clinical and ophthalmological presentations.  

Sanzgiri, R, Wilson, M, McCarville, M, Helton, K, Imaging, Clinical and Pathological Features of Pediatric Medulloepithelioma: Four Cases and Review of the Literature.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12033540.html