Ravi Rajnikant Desai BS, Presenter: Nothing to Disclose

Namita Sharma Gandhi MD, Abstract Co-Author: Nothing to Disclose

Sankaran Shrikanthan MD, Abstract Co-Author: Nothing to Disclose

Raghunandan Vikram MBBS, FRCR, Abstract Co-Author: Nothing to Disclose

Chitra Viswanathan MD, Abstract Co-Author: Nothing to Disclose

Steve Shih-Lin Huang MD, Abstract Co-Author: Nothing to Disclose

Shetal N. Shah MD, Abstract Co-Author: Research Consultant, Dendreon Corporation

To highlight the complementary role of PET-CT at initial treatment strategy (i.e. detection, localization, staging) as well as subsequent treatment strategies (restaging and monitoring therapy) for urogynecologic malignancies. 

FDG-PET-CT is limited in uro-oncology applications due to FDG urinary excretion. Novel PET radiotracers such as C11- acetate, F18- fluoride are under investigation. These have high specificity and sensitivity in differentiating BPH from prostate cancer. F18-fluoride PET-CT has more sensitivity and specificity than MDP bone scan in detecting bone metastases in high risk prostate cancer. FDG PET-CT helps in staging and restaging of renal cell carcinoma and is valuable in detecting unsuspected occult metastases for urinary bladder carcinoma. Most gynecologic malignancies are staged using clinical FIGO system with no nodal information inluded. For cervical carcinoma, PET-CT helps in identifying skip nodal metastases to the retroperitoneal and supraclavicular nodes, and in radiotherapy planning. For endometrial carcinoma, PET-CT outperforms CT in detecting pelvic and distal metastases, can guide percutaneous intervention and help with disease surveillance.  

PET-CT imaging has potential applications in detection, staging, restaging, and recurrence monitoring of the uro-gynecologic malignancies.

Desai, R, Gandhi, N, Shrikanthan, S, Vikram, R, Viswanathan, C, Huang, S, Shah, S, Urogynecologic PET/CT: Current Roles and Updates.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12033369.html