Kevin Chikai Ma BS, Presenter: Nothing to Disclose

Nakul Reddy, Abstract Co-Author: Nothing to Disclose

Lilyana Amezcua MD, Abstract Co-Author: Consultant, Biogen Idec Inc Consultant, Bayer AG Consultant, Teva Pharmaceutical Industries Ltd Consultant, Merck KGaA Consultant, Pfizer Inc Advisory Board, Biogen Idec Inc Advisory Board, Bayer AG Advisory Board, Teva Pharmaceutical Industries Ltd Advisory Board, Pfizer Inc Advisory Board, Merck KGaA Speaker, Biogen Idec Inc Speaker, Bayer AG Speaker, Teva Pharmaceutical Industries Ltd Speaker, Merck KGaA Speaker, Pfizer Inc

Brent Julius Liu PhD, Abstract Co-Author: Nothing to Disclose

Last year at RSNA we presented a multiple sclerosis (MS) eFolder as an integrated imaging-informatics based system to provide functionalities to clinical and research environments. The eFolder system combines patients’ clinical data, radiological images and computer-aided lesion detection and quantification results to aid in longitudinal tracking, data mining, decision support, and other clinical and research needs. To demonstrate how this system can be iimplemented in an enterprising imaging environment such as a large-scale multi-site MS clinical trial, we present a eFolder system simulation to streamline imaging and clinical data flow with postprocessing (CAD) steps by following DICOM standards and IHE initiatives. The integrated system workflow is designed according to IHE postprocessing workflow profile to further realize MS eFolder’s use in a real-world situation.

The MS eFolder system is integrated with a real-world clinical environment according to the IHE post-processing workflow profile. The success of the integration both demonstrates the usefulness of the eFolder system and provides an example of how to use such system in a real-world situation via IHE guidelines. 

We successfully demonstrate using IHE’s workflow profile in a real-world clinical environment using an imaging informatics-based MS eFolder. The integrated workflow helps data managing, data mining, viewing and storage, and perform a quantitative analysis that otherwise not available without post-processing workflow.

The system contains components outlined in the IHE post-processing workflow. The imaging modality simulator sends a set of MRI brain DICOM studies into the eFolder system. The system provides an imaging archive for storage. The images are then sent to the CAD workstation to perform post-processing, and the completed DICOM-compliant report is stored in the archive. A web-based GUI is used to query/retrieve and display the imaging data, post-processing results, and patient’s data stored in the patient record. The eFolder GUI also monitors data flow of patients’ images to ensure delivery of data among each component in the eFolder.

Ma, K, Reddy, N, Amezcua, L, Liu, B, Bridging the Gap between Post-processing Innovations and Real-World Clinical Use: The Utilization of an eFolder with Embedded IHE Workflow Profile for MS Clinical Trials.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12029282.html