Sikandar Mohd Shaikh DMRD, Presenter: Nothing to Disclose

The aim of this study was to compare the relative contribution of F-18-FDG-PET/CT and WBMRI in the evaluation of Haematologic malignancies patients

Twenty patients ( 11 women, 9 men ; age 55.3 +/- 9.9 years ; remission status, 11 complete remission, 9 partial remission ) during follow-up were retrospectively studied. All patients underwent Whole body F-18-FDG-PET/CT and WBMRI within 1 month of each other F-18-FDG-PET/CT was acquired using a standard protocol. WBMRI was acquired at 1.5T pre and post contrast sequences acquired. Bone involvement observed by MBMRI was characterized in pattern, size and contrast enhancement, bone involvement observed by F-18-FDG-PET/CT was characterized in terms of pattern, size and tracer accumulation.

F-18-FDG-PET/CT detected a total of 10 lesions in 6 patients. WBMRI detected a total of 97 discrete lesions in 12 patients. On a per patient basis, F-18-FDG-PET had a sensitivity of 50 %, a specificity of 91 %, positive predictive value of 67 %, and a negative predictive value of 83 %, WBMRI had a sensitivity of 88 % a specificity of 41%, a positive predictive value of 35 % and a negative predictive value of 90 %, Comparison of F-18-FDG-PET and WBMRI findings revealed concordant results in only (4.7 %) of the 102 lesions.

Both F-18-FDG-PET/CT and WBMRI can contribute a more comprehensive evaluation of hematologic malignancies in patients adding information and act as complimentary to each other.

F-18-FDG-PET/CT is more suitable for early response detection of bone involvement, however WBMRI may be an additional predictive marker for long-term follow-up.

Shaikh, S, F-18-FDG PET/CT vs Whole Body MR Imaging in the Evaluation of Haematologic Malignancies.  Radiological Society of North America 2012 Scientific Assembly and Annual Meeting, November 25 - November 30, 2012 ,Chicago IL. http://archive.rsna.org/2012/12023747.html