Caroline Parlier MD, Presenter: Nothing to Disclose

Bassam Hamze MD, Abstract Co-Author: Nothing to Disclose

Antoine A. Feydy MD, Abstract Co-Author: Nothing to Disclose

Philippe Orcel, Abstract Co-Author: Nothing to Disclose

Jean-Denis Laredo MD, Abstract Co-Author: Research Consultant, Cardinal Health, Inc Research Consultant, Laurane Medical Research Consultant, onTargetjobs Research grant, SERVIER

To investigate the safety and efficiency of balloon kyphoplasty (BK) for osteolytic vertebral compression fractures due to multiple myeloma or metastatic cancer

From January 2007 to January 2009 ,19 consecutive patients (mean age :59 years) with malignant collapse (30 vertebrae) from T5 to L5 were treated by BK. Radiographs, CT and MR images were obtained before BK, radiographs and CT at one and 360 day FU. Clinical evaluations before and after BK (15-90-180 and 360 day FU) included Visual Analog Scale (VAS) for pain and mobility. Radiological evaluation included kyphosis angle before and after BK.

No complication was related to KB. No patient had to be reoperated on for tumor progression. Asymptomatic cement leakages were observed in 12 patients (vein :7, disc:9, epidural mass:1, paravertebral mass 2) Mean preoperative VAS for pain and mobility were respectively 67 and 62 mm. Mean postoperative VAS were respectively at 15;90;180 and 360 day FU for pain: 25,23,11,21 and for mobility:28,27,14,16. 14 patients had a VAS< to 3.5 at 15 day FU . One patient had delayed improvement at 90 day FU with a VAS score of 1. 2 patients deceased at 7 and 60 day FU. 2 patients had no significant improvement of VAS score . kyphotic angle was not significantly modified by KB at FU. Two patients needed further surgery: One patient because of kyphosis angle worsening not related to kyphoplasty and the other one because of persisting nerve root pain which was already present prior to BK.

BK is a safe and effective method in treating osteolytic vertebral compression fractures vertebral due to myeloma and metastatic lesion which can relieve pain and improve mobility as well as minimize the incidence of cement leakage

BK is a safer methodfor treatment of  osteolytic malignat vertebral compression   in case of cortical destruction  and is an effective method to relieve pain and improve mobility.

Parlier, C, Hamze, B, Feydy, A, Orcel, P, Laredo, J, Evaluation of the Safety and the Efficiency of Balloon Kyphoplasty for Osteolytic Vertebral Compression Fractures Due to Multiple Myeloma or Metastatic Cancer.  Radiological Society of North America 2011 Scientific Assembly and Annual Meeting, November 26 - December 2, 2011 ,Chicago IL. http://archive.rsna.org/2011/11034498.html