Ki Jeong Park MD, Presenter: Nothing to Disclose

So Young Yoo MD, Abstract Co-Author: Nothing to Disclose

Ji Hye Kim MD, PhD, Abstract Co-Author: Nothing to Disclose

Hong Eo, Abstract Co-Author: Nothing to Disclose

Tae Yeon Jeon MD, Abstract Co-Author: Nothing to Disclose

Kyoung Doo Song MD, Abstract Co-Author: Nothing to Disclose

To investigate the correlation between the mound morphology on US after subureteral injection of Deflux for correction of vesicoureteral reflux (VUR) and the outcome.

A total of 36 patients (M:18, F:18, age range: 24-194 months, mean age: 68 months) and 56 refluxing ureter units treated with a endoscopic subureteral injection of Deflux by a single physician were enrolled for this retrospective study. All patients had grade 1~4 VUR unilaterally (16/36) or bilaterally (20/36) preoperatively and underwent postoperative voiding cystourethrography (VCUG) and kidney/bladder US with mean interval between the injection and each exam, 47 and 34 days, respectively. According to appearance of the ureterovesical junction (UVJ) on US, the mound morphology was graded as 1(bulging mound formation at the UVJ), 2(visible substance in the far distal ureter without mound formation at the UVJ) and 3 (neither 1 nor 2). The outcome was graded as 1 (no VUR), 2 (downgrading of VUR) and 3 (persistent VUR) on postoperative VCUG.

Of the ureters with grade 1 mound morphology (n= 25), VUR disappeared in 22 (88%), downgraded in 1 (4%) and persisted in 2 (8%). Of the ureters with grade 2 mound morphology (n= 13), VUR disappeared in 7 (54%), downgraded in 4 (31%) and persisted in 2 (15%). Of the ureters with grade 3 mound morphology (n=18), VUR disappeared in 11 (61%), downgraded in 2 (11%) and persisted in 5 (28%). Statistically significant correlation was found between the mound morphology on US and the outcome (P value = 0.032).

The mound morphology on US after subureteral injection of Deflux was statistically correlated with the outcome of VUR. We suggest that US may be helpful for predicting the outcome after treatment of VUR.

US may be helpful for predicting the outcome after treatment of VUR.

Park, K, Yoo, S, Kim, J, Eo, H, Jeon, T, Song, K, US after Subureteral Injection of Deflux for Vesicoureteral Reflux: Correlation between Mound Morphology and Outcome.  Radiological Society of North America 2011 Scientific Assembly and Annual Meeting, November 26 - December 2, 2011 ,Chicago IL. http://archive.rsna.org/2011/11034311.html