Yu Mee Sohn, Presenter: Nothing to Disclose

Min Jung Kim MD, Abstract Co-Author: Nothing to Disclose

Eun-Kyung Kim, Abstract Co-Author: Nothing to Disclose

The purpose of this study was to evaluate the sensitivity of bilateral whole breast sonography (BWBS) added to mammography to detect the additional lesions as well as the index lesion in patient with invasive lobular carcinoma (ILC) and to evaluate the impact of BWBS on strategy of surgical treatment and cancer staging.

We retrospectively reviewed mammographic and sonographic records of 107 patients with 130 proven ILCs during November 2002 to November 2009 in two medical centers. We evaluated the sensitivity of mammography and BWBS for the detection of respective lesions including additional lesions as well as index lesions. We evaluate the impact of BWBS to compare the surgical treatment and the breast cancer staging between cases with index lesion alone and cases with BWBS-detected additional lesions as well as index lesion.

The overall sensitivity was 77.4 % (106/137 lesions) in mammography and 97.8 % (134/137 lesions) in BWBS (p < 0.001). The sensitivity of BWBS for both index lesions (100.0%, 107/107 lesions) and the additional lesions (90.0 %, 27/30 lesions) are higher than them of mammography (85.1 %, 91/107 lesions; 43.3 %, 13/30 lesions, respectively, p < 0.001). As for the single index lesions by mammography and US and additional lesions detected by US alone, single index lesions showed more N0 stage (62.9 %) than additional lesions (26.7 %) (p = 0.0195). There was significant difference between the surgery method (mastectomy vs breast conservation surgery) and the presence of additional lesions (single index lesions vs additional lesions) (p = 0.0153)

BWBS has a higher sensitivity than mammography in the detection of index lesions and additional lesions of the ILC. The results of this study suggest BWBS improved the detection of ILC that can be missed by mammography alone and the detection of additional malignancy could have association with the strategy of surgical treatment and predict the higher N staging.

BWBS improved the detection of ILC that can be missed by mammography alone.

Sohn, Y, Kim, M, Kim, E, Impact of Preoperative Bilateral Whole Breast Sonography in Patients with Invasive Lobular Carcinoma: The Results with Two Medical Centers.  Radiological Society of North America 2011 Scientific Assembly and Annual Meeting, November 26 - December 2, 2011 ,Chicago IL. http://archive.rsna.org/2011/11034268.html