Jennifer Jaroni MD, Presenter: Nothing to Disclose

Marcus R. Settles PhD, Abstract Co-Author: Nothing to Disclose

Ken Herrmann, Abstract Co-Author: Nothing to Disclose

Ambros Johannes Beer MD, Abstract Co-Author: Research funded, Pieris AG Speaker, Siemens AG

Ernst J. Rummeny MD, Abstract Co-Author: Nothing to Disclose

Armin Michael Huber MD, Abstract Co-Author: Nothing to Disclose

To determine the accuracy of three-dimensional (3D) kt-broad-use linear acquisition speed-up technique (BLAST) accelerated MRI (kt-BLAST) for the assessment of LV volumes and mass standard compared to segmented multiple breath-hold cine imaging.  

55 patients were included. In each patient a standard multislice cine steady-state free precession (SSFP) sequence was performed with complete ventricular coverage during multiple breath-holds (temporal resolution 47 msec, voxel size 1.25 x 1.25 x 8 mm3). In addition, two kt-BLAST-accelerated 3D sequences with complete ventricular coverage were acquired kT1 (TR 3.2 msec, TE 1.6 msec, temporal resolution 57 msec, voxel size 1.25 x 1.25 x 4 mm3) and kT2 (TR 3.2 msec, TE 1.6 msec, temporal resolution 57 msec, voxel size 1.25 x 1.25 x 8 mm3) during a single breath-hold after a separate breath-hold for a training scan. For comparison of SSFP and kt-BLAST, the following LV parameters were determined: EF, EDV, ESV and LV mass.

The EF was slightly underestimated by the kT1 (47 %) and kT2 (48 %) compared to the reference sequence (53 %). All parameters showed high correlation of the kT-BLAST sequences and the reference sequence (r=88 to r=0.98, r<0.001). The relative mean difference for KT1/KT2 compared to the reference sequence was 0.11/0.09 for the EDV, -0.073/-0.086 for the EDV, 0.044/-0.051 for the ESV and 0.085/0.12 for the LV mass.

3D kt-BLAST-accelerated MRI enabled to determine the LV parameters with high correlation compared to the reference sequence. EF was slightly underestimated, LV mass slighlty overestimated.

Fast 3D kTBLAST-accelerated Cine MRI allows for a single breathhold data acquisition and determination of global LV functional parameters with mean differences compared to the reference technique, a s

Jaroni, J, Settles, M, Herrmann, K, Beer, A, Rummeny, E, Huber, A, Three-dimensional Magnetic Resonance Imaging Using Single Breath-hold kt-BLAST for Assessment of Global Left Ventricular Functional Parameters.  Radiological Society of North America 2011 Scientific Assembly and Annual Meeting, November 26 - December 2, 2011 ,Chicago IL. http://archive.rsna.org/2011/11012167.html