RSNA 2011 

Abstract Archives of the RSNA, 2011


SSC01-06

Assessment of Left Ventricular Myocardial Scar in Coronary Artery Disease by Three-dimensional Magnetic Resonance Imaging

Scientific Formal (Paper) Presentations

Presented on November 28, 2011
Presented as part of SSC01: Cardiac (Myocardial Infarction)

Participants

Gang Yin BS, Presenter: Nothing to Disclose
Shihua Zhao MD, Abstract Co-Author: Nothing to Disclose
Minjie Lu, Abstract Co-Author: Nothing to Disclose
Shiliang L Jiang, Abstract Co-Author: Nothing to Disclose
Huaibing Cheng, Abstract Co-Author: Nothing to Disclose
Ning Ma, Abstract Co-Author: Nothing to Disclose
Yan Zhang MD, Abstract Co-Author: Nothing to Disclose

PURPOSE

To compare a new free-breathing 3D phase sensitive inversion recovery (PSIR) Turbo FLASH pulse sequence with conventional 2D PSIR Turbo FLASH for detecting left ventricular myocardial scar in patients with coronary artery disease (CAD).

METHOD AND MATERIALS

Twenty-three patients with prior myocardial infarction were assessed using a segmented 2D and 3D PSIR Turbo FLASH sequence for late gadolinium enhancement (LGE) imaging in cardiac magnetic resonance (CMR) ,respectively. All images were evaluated by two independent radiologists. Overall image quality was divided into four grades (0 = poor,nondiagnostic;1 = fair, diagnostics may be impaired;2 = good, some artifacts but not interfering in diagnostics;3 = excellent,no artifacts). The hyperenhanced area, location and volume were quantitatively compared between 2D and 3D.

RESULTS

No differences were noted in the overall image quality, the hyperenhanced area and location. The mean hyperenhanced volume was significantly greater in 3D PSIR than that in 2D PSIR (2D vs 3D,(23.46±10.61)cm3 vs (31.65±13.86)cm 3,t=-2.25,P=0.03). There was strong correlation in the hyperenhanced volume between 2D PSIR and 3D PSIR (r=0.940,P <0.001;y=2.851+1.228x,R2=0.883).

CONCLUSION

Free-breathing 3D PSIR Turbo FLASH is a promising approach to accurately assess left ventricular myocardial scar,especially in scar quantification.

CLINICAL RELEVANCE/APPLICATION

We demonstrated the free breathing 3D PSIR approach is a suitable method for the assessment of left ventricular scar particularly for scar quantifcation.

Cite This Abstract

Yin, G, Zhao, S, Lu, M, Jiang, S, Cheng, H, Ma, N, Zhang, Y, Assessment of Left Ventricular Myocardial Scar in Coronary Artery Disease by Three-dimensional Magnetic Resonance Imaging.  Radiological Society of North America 2011 Scientific Assembly and Annual Meeting, November 26 - December 2, 2011 ,Chicago IL. http://archive.rsna.org/2011/11011720.html