Le Wang, Presenter: Nothing to Disclose

Bin Liu MD, Abstract Co-Author: Nothing to Disclose

Yongqiang Yu MD, Abstract Co-Author: Nothing to Disclose

Xingwang Wu, Abstract Co-Author: Nothing to Disclose

Yong Zhou MD, Abstract Co-Author: Nothing to Disclose

Shuai Zhang, Abstract Co-Author: Nothing to Disclose

Yun Shen PhD, Abstract Co-Author: Employee, General Electric Company Researcher, General Electric Company

Wang Jie, Abstract Co-Author: Nothing to Disclose

Xiaohu Li, Abstract Co-Author: Nothing to Disclose

To assess the feasibilty of quantification of iodine at pulsating status with gemstone spectral imaging(GSI).

The pulsating phantom with frequency of 15 bpm(beat per minute), amplitude of 10mm, containing nine test tubes of solution which varied in iodine concentrations(0.4,0.7,2.5,10,20,30,50 and 100mgI/cc) underwent GSI examination with spectral CT (Discovery CT750 HD) at the tube speed of 0.6s/rotation, 0.8s/rotation and 1.0s/rotation, respectively. All data were transferred to GSI viewer to acquire iodine-based images at which the iodine concentrations were measured with the same size of regions of interest at the same level. The relation and discrepancy between measured iodine concentrations and real iodine concentrations were compared.

At the tube speed of 0.8 s/rotation and 1.0 s/rotation, the measured concentrations were significant correlated to the real concentrations (r2=0.9986 and r2=0.9990) without significant difference between these two values(p=0.8168 and p=0.8096). However significant statistical difference was found between the measured values and the real values at the tube speed of 0.6 s/rotation (p=0.0427) with linear correlation between these two(r2=0.9976).

GSI of spectral CT is a reliable method to accurately quantify iodine with bobbing at the tube speed of 0.8 s/rotation and 1.0 s/rotation. But it fail in precise determination of iodine concentration at the tube speed of 0.6 s/rotation. Owing to accurate quantification of iodine, GSI might be useful to characterize and differentiate tissues and lesions.  

GSI can differentiate material composition even in pulsating status.

Wang, L, Liu, B, Yu, Y, Wu, X, Zhou, Y, Zhang, S, Shen, Y, Jie, W, Li, X, Can Gemstone Spectral Imaging Accurately Determine Iodine Concentration? A Pulsating Phantom Study.  Radiological Society of North America 2011 Scientific Assembly and Annual Meeting, November 26 - December 2, 2011 ,Chicago IL. http://archive.rsna.org/2011/11007702.html