Garry Evan Gold MD, MSEE, Presenter: Consultant, Zimmer Holdings, Inc Consultant, ICON plc Research support, General Electric Company

Magnetic resonance imaging (MRI) is a powerful tool for the study of osteoarthritis. Conventional MRI detects cartilage damage after tissue loss has occurred, when the disease process may be irreversible. New MRI techniques that are sensitive to cartilage glycoaminoglycan (GAG) may be useful in the diagnosis of early osteoarthritis, before tissue loss has occurred. These techniques include delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC), T1p mapping, glycosaminoglycan chemical exchange saturation transfer (gagCEST) imaging, and 23Na Imaging. Techniques to detect early derangements in the collagen fiber architecture such as diffusion-weighted MRI may also be helpful in studying early disease. This session will discuss these and other new exciting methods in cartilage MRI.

Gold, G, Musculoskeletal Keynote Speaker: gagCEST, 23Na Imaging, Collagen Fiber Arrangement of Knee Cartilage.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9020277.html