Tulin Ozturk, Abstract Co-Author: Nothing to Disclose

Zulkif Bozgeyik, Presenter: Nothing to Disclose

Yusuf Ozkan, Abstract Co-Author: Nothing to Disclose

Erkin Ogur, Abstract Co-Author: Nothing to Disclose

The aim of this study was to evaluate the usefulness of diffusion-weighted magnetic resonance imaging (DWMRI) for differentation of between graves disease and hashimoto thyroiditis.

Fifty patients (27 Graves diseases and 23 Hashimoto thyroiditis) and twenty healthy volunteers were examined using T1, T2 and DWMRI. The patients were diagnosed on the basis of physical findings and the results of thyroid function tests and serological tests. Circular ROIs were positioned on the bilateral thyroid lobes and isthmus at the level of the upper and lower poles. All measurements were repeated three different b values including 100, 600 and 1000 s/mm2 in all cases. ADC (Apparent diffusion coefficient) maps were calculated automatically with the MR system and ADC values are expressed in square millimeters per second.

Mean ADC values were 2.93 x 10-3, 1.97 x 10-3 and 1.62 x 10-3 mm2/s in the healthy volunteers; 3.47 x 10-3, 2.25 x 10-3 and 1.64 x 10-3 mm2/s in Graves diseases; 2.53 x 10-3, 1.76 x 10-3, 1.28 x 10-3 mm2/s in Hashimoto thyroiditis for b100, b600 and b1000, respectively. The ADC values of the Graves diseases were higher than healty volunteers and Hashimoto thyroiditis. The patients with Hashimoto thyroiditis had lower ADC values than Graves diseases and healthy volunteers. ADC values were statistically significant for differentation of between Hashimoto thyroiditis and Graves diseases all b values (p<0.05).

DWMRI is fast sequence and does not require contrast agent. Quantitative assessment of the lesion is possible using ADC map. So, DWMRI may be useful differentiation of the Hashimoto thyroiditis and Graves diseases.

 dealing with functional MRI

Ozturk, T, Bozgeyik, Z, Ozkan, Y, Ogur, E, The Role of Diffusion-weighted MR Imaging for Differentiation between Graves Disease and Hashimoto Thyroiditis.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9014835.html