Yun Peng MD, Presenter: Nothing to Disclose

To retrospectively compare contrast-enhanced multislice computed tomography (MSCT) and ultrasound (US) imaging for the assessment of cystic renal masses in children using the Bosniak classification system.

Twenty-two consecutive patients (age 1 month to 5.2 years, mean 2.4 years) with 24 cystic renal masses (7 benign, 17 malignant) pathologically confirmed after surgical resection underwent both MSCT and US imaging, and were retrospectively analyzed using the Bosniak classification. A senior and a junior radiologist retrospectively and independently reviewed imaging findings. The sensitivity, specificity, positive predictive value and negative predictive values of MSCT and US were assessed using diagnostic statistics. The statistical significance of differences was determined by the McNemar test.

Both radiologists accurately predicted lesions of categories I and IV with the Bosniak classification using MSCT and US. All masses classified as Bosniak class I and II were proven to be benign, and all malignant lesions were correctly characterized in all cases both on ultrasound images and on the contrast-enhanced CT (CECT) images. Two benign multilocular cystic nephromas and one multicystic dysplastic kidney were classified into category III or even IV based on the classification scheme because of their multilocular nature and thick septation. The diagnostic accuracy of CECT was slightly better than ultrasound (CECT vs. US: senior reader, 92% vs. 88%; junior reader, 88% vs. 83%). However, there was no statistically significant difference between the two sets (p>0.05). The two radiologists had perfect inter-observer agreement on the two modalities.

Both MSCT and US provide highly accurate diagnosis for the malignant renal cystic masses in children using the Bosniak classification system, but assessment of benign masses still needs improvement.

Understanding the characteristic appearance of cystic renal masses in children may lead to an accurate diagnosis and optimize patient management.

Peng, Y, Assessment of Cystic Renal Masses in Children: Comparison of Multislice Computed Tomography and Ultrasound Imaging Using the Bosniak Classification System.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9012876.html