Yingru Zhao MD, Presenter: Nothing to Disclose

G. H. De Bock, Abstract Co-Author: Nothing to Disclose

Monique D. Dorrius, Abstract Co-Author: Nothing to Disclose

Lars Bornemann MS, Abstract Co-Author: Nothing to Disclose

Jan-Martin Kuhnigk PhD, MS, Abstract Co-Author: Nothing to Disclose

Rob Van Klaveren, Abstract Co-Author: Nothing to Disclose

Matthys Oudkerk MD, PhD, Abstract Co-Author: Nothing to Disclose

To compare two software packages on volumetric measurement and evaluate their influence on management of pulmonary nodules detected at baseline scans

Twenty-two participants were randomly selected from Nelson study, a lung cancer screening project. Nodules were measured by two semi-automated software packages (Syngo LungCARE and OncoTREAT) and evaluated by two readers with each software system. Nodules were classified by size (Cat A: < 50 mm3, Cat B: 50-500 mm3, Cat C: >500 mm3). Nodule managements were arranged according to their volume categories (Cat A: annual repeat scan, Cat B: repeat scan after 3 months, Cat C: refer to pulmonologist).

Of 230 nodules found at baseline scans, 228 could successfully be measured with both two software packages. The mean and median volume was 87.9 mm3 and 60 mm3 by using OncoTREAT, 60 mm3 and 40 mm3 by using LungCARE. 177 (77.6%) nodules had agreement in volume categories with the two systems. 94 were Cat A, 81 were Cat B and 2 were Cat C. 49 were evaluated as Cat A nodules in LungCARE but Cat B in OncoTREAT. 2 Cat B nodules measured by the LungCARE system were regarded as Cat A nodules by using OncoTREAT. No divergence in evaluating Cat C nodule was shown between the two packages.

The two software packages had significant difference in volumetric measurement. Measuring by OncoTREAT system, more nodules would be repeat scanned after 3 months. Nodule management at baseline could be influenced by using different software packages.

the influence of volumetric measurement software on management of pulmonary nodules

Zhao, Y, De Bock, G, Dorrius, M, Bornemann, L, Kuhnigk, J, Van Klaveren, R, Oudkerk, M, Influence of Software Volumetric Evaluation on Management of Pulmonary Nodules Detected at Baseline Scans in Nelson Study.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9010177.html