Yoko Satoh, Presenter: Nothing to Disclose

Tomoaki Ichikawa MD, PhD, Abstract Co-Author: Nothing to Disclose

Utaroh Motosugi MD, Abstract Co-Author: Nothing to Disclose

Kazufumi Kimura, Abstract Co-Author: Nothing to Disclose

Hironobu Sou MD, Abstract Co-Author: Nothing to Disclose

Tsutomu Araki MD, Abstract Co-Author: Nothing to Disclose

To compare the diagnostic performance of F-18 fluorodeoxyglucose positoron emission tomography/CT (PET/CT), MRI with and without diffusion-weighted images (DWI), and contrast-enhanced multidetector-row CT (CE-MDCT) for detecting peritoneal disseminations.

We retrospectively evaluated 107 patients for PET/CT and 130 for MRI and CE-MDCT. Finally, 26 and 23 patients were found to have peritoneal dissemination in each group, respectively. All images were independently evaluated by two each radiologists with 5-points grading system. The results of PET/CT, T1 and T2-weighted MRI without DWI (CMRI), CMRI with DWI (b=1000 sec/mm2) (DW-MRI), and CE-MDCT were compared on patient-by-patient basis and lesion-by-lesion basis by a receiver operating characteristic (ROC) analysis. Sensitivity, specificity, and, positive predictive value (PPV) were also calculated and compared by chi-square test.

On patients-by-patients analysis, the Az values of CMRI (0.88) were significantly lower than those of the other image sets (CE-MDCT, 0.91; DW-MRI, 0.93; PET/CT, 0.97). The sensitivity of PET/CT (94%) was significantly higher than that of CMRI (70%. The specificities of each image set showed no significant difference. On lesion-by-lesion analysis, CMRI had significantly lower sensitivity (56%) compared to the other image sets (CE-MDCT, 76%; DW-MRI, 84%; PET/CT, 89%). The PPV of PET/CT (93%) was significantly higher than those of the other 3 image sets (CE-MDCT, 73%; DWI-MRI, 70%; DW-MRI, 72%).

It is useful to add DWI to CMRI for detecting peritoneal dissemination. However, PET/CT showed the highest PPV compared to the other modalities.

It is useful to add DWI to conventional MRI for detecting peritoneal dissemination. However, PET/CT is the most reliable modality showing the highest PPV compared to the other modalities.

Satoh, Y, Ichikawa, T, Motosugi, U, Kimura, K, Sou, H, Araki, T, Diagnosis of Peritoneal Dissemination: Comparison of 18F-PET/CT, Diffusion-weighted MR Imaging, and Contrast-enhanced MDCT.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9009723.html