Qinyi Dai, Presenter: Nothing to Disclose

Zhaoqi Zhang, Abstract Co-Author: Nothing to Disclose

Yi He MD, Abstract Co-Author: Nothing to Disclose

Lixin Jin, Abstract Co-Author: Employee, Siemens AG

Jing An, Abstract Co-Author: Nothing to Disclose

To examine the accuracy of whole-heart coronary magnetic resonance angiography ( WH CMRA) for the evaluation of coronary artery stenosis.

Eighty-eight patients underwent navigator-gated WH CMRA without contrast material (1.5T MAGNETOM Sonata, Siemens, Germany). WH CMRA was acquired using a 3D ECG-triggered, navigator-gated, fat-suppressed, T2-prepared steady state free precession sequence. Image quality of WH CMRA images was evaluated on a segmental basis using a 4-point scale (1-not visible; 2- moderate; 3-good; 4-excellent). MR image analysis was performed by 2 radiologists who were blinded to CAG. Segments with a score of 1 were excluded from analysis. The diagnostic performance of WH CMRA in detecting stenosis was compared with CAG as stenosis ≥50% in luminal narrowing.

① 79 patients were successfully completed WH CMRA exam, and 42 of them compared  CAG. ② 79 patients( 79/88，89.8%; 54 male; mean age 58 years) were completely successfully performed within 13.28±4.33 minutes (range 6.23~28 minutes), heart rate 67±8 (range 44~93) bpm，BMI 25.9±3.2 (range 19.2~34.2)； ③ Qualitative image analysis was performed by 79 cases as score 1 for 4 cases (4/79，5.1%) and score 2-4 for other 75 cases； ④ The acquisition of CAG was completed in 42 of 79 patients, with acquisition time 13.5±4.6 min and image quality 3.2±0.9 on average, heart rate 67±10 (range:44~93) bpm. All patients received conventional angiography (5±2) days before or after the MR exam. ⑤ A total of 355 segment were including and the sensitivity, specificity, PPV, NPV and accuracy of MR coronary angiography for detecting coronary stenosis on segment-based analysis were 88.6%、94.9%、70.9%、98.3% and 94.1%,These values on vessel-based and patient-based were 87.9%、90.4%、70.7%、96.6%、89.9% and 90.5%、66.7%、73.1%、87.5%、78.6%, respectively ( Figure 1).  

As a non-invasive diagnostic method , WH CMRA allows detection of coronary arterial stenosis with moderate sensitivity and high NPV.

As a noninvasive method, whole-heart coronary MRA (WH CMRA) detects coronary artery disease (CAD) without the use of contrast agent based on the assessment of luminal narrowing.

Dai, Q, Zhang, Z, He, Y, Jin, L, An, J, Whole-Heart Coronary Magnetic Resonance Angiography for the Detection of Coronary Stenosis.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9009469.html