RSNA 2010 

Abstract Archives of the RSNA, 2010


SST16-07

Radiofrequency Ablation with and without Superficial Saline Injection to Prevent Skin Burn in a Rabbit Model

Scientific Formal (Paper) Presentations

Presented on December 3, 2010
Presented as part of SST16: Vascular/Interventional (Oncologic Interventions in the Kidney, Lung, and beyond: VIR—Oncology)

Participants

Jung Hee Shin MD, Presenter: Nothing to Disclose
Boo-Kyung Han MD, PhD, Abstract Co-Author: Nothing to Disclose
Eun Young Ko MD, PhD, Abstract Co-Author: Nothing to Disclose
Ko Woon Park MD, Abstract Co-Author: Nothing to Disclose
Shin Young Kim, Abstract Co-Author: Nothing to Disclose
Jeung Hee Moon, Abstract Co-Author: Nothing to Disclose
Eun Young Yoo, Abstract Co-Author: Nothing to Disclose

PURPOSE

The aim of this study was to determine whether radiofrequency ablation with superficial saline injection can minimize thermal injury of skin without the influence of therapeutic efficacy.

METHOD AND MATERIALS

Twelve percutaneous RF ablation procedures were performed in the thighs of 6 rabbits (control, n=6, right thigh; experimental, n=6, left thigh) using an internally cooled electrode with 1 cm active tip. The ablation was performed in the most superficial area of thigh muscle. In the experimental group, saline with 1 cc in amount before ablation was injected at the tissue layer between skin and ablated muscle. The duration and energy for ablation were the same in the control and the experimental group. Rabbits were sacrificed 2 days after ablation and were compared for gross skin state and histopathological findings after ablation.

RESULTS

The degree of thermal coagulation of the muscle was similar in both groups at pathology. Grossly, skin redness was mild in the experimental group but moderate in the control group. Of 6 rabbits, five showed more frequently histopathological changes including inflammatory reaction, interruption of collagen fibers, injury of skin adnexa and fibrosis in the control group compared to experimental group. However, there was no difference in changes between two groups in one. One rabbit with a higher energy had the partially dissected epidermis only in the control group.

CONCLUSION

Radiofrequency ablation with superficial saline injection can prevent skin burn and provide equivalent therapeutic efficacy for ablating superficial lesions.

CLINICAL RELEVANCE/APPLICATION

Radiofrequency ablation for benign thyroid tumors with cosmetic problem is indicated, but it is important to avoid skin burn during the ablation of superficial lesion.

Cite This Abstract

Shin, J, Han, B, Ko, E, Park, K, Kim, S, Moon, J, Yoo, E, Radiofrequency Ablation with and without Superficial Saline Injection to Prevent Skin Burn in a Rabbit Model.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9009391.html