Abstract Archives of the RSNA, 2010
SSA14-03
Utility of Time-resolved Contrast-enhanced Magnetic Resonance Angiography in Evaluation of Peripheral Vascular Malformations
Scientific Formal (Paper) Presentations
Presented on November 28, 2010
Presented as part of SSA14: ISP: Musculoskeletal (Tumors and Soft Tissue)
Aiden Moktassi MD, Presenter: Nothing to Disclose
Ravi Menezes PhD, Abstract Co-Author: Nothing to Disclose
Jeff Jaskolka, Abstract Co-Author: Nothing to Disclose
Robert Bleakney MBChB, FRCPC, Abstract Co-Author: Nothing to Disclose
To assess the impact of adding time-resolved, contrast-enhanced MR angiography (trMRA) to routine anatomic MR imaging in the assessment of peripheral vascular malformations.
Between March 2008 and September 2009, 50 consecutive patients referred for assessment of peripheral vascular malformations underwent conventional anatomic MRI and trMRA. All MR studies were retrospectively reviewed, independently by 2 fellowship-trained musculoskeletal radiologists, blinded to clinical information and other imaging studies. At MR imaging review, lesions were categorized as either low flow or high flow. Categorization was performed initially using conventional anatomic MRI alone and at a subsequent sitting using trMRA. If opinions differed, a third read was performed where conclusion was reached by consensus. Inter-observer agreement was evaluated with Kappa statistics. Diagnostic performance of MR imaging for differentiating low-flow from high-flow vascular malformations was determined with and without trMRA. The reference standard was a consensus opinion of two experts based on all available imaging studies, clinical notes, treatment information and pathology reports.
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Sensitivity, specificity, and accuracy of conventional MRI in differentiating low-flow from high flow lesions were 53%, 80%, and 72%. With the addition of trMRA, sensitivity, specificity and accuracy increased to 80% (p=0.125), 97% (p=0.031), and 92% (p=0.002) respectively. MRI without MR angiography showed substantial inter-observer agreement (K =0.775), which increased to near perfect agreement (K=0.913), with the addition of trMRA.
Time-resolved MR angiography is valuable in the assessment of peripheral vascular malformations, resulting in improved inter-observer agreement as well as increased specificity and accuracy in the characterization of peripheral vascular malformations.
Time-resolved MR angiography can be valuable in the assessment of peripheral vascular malformations.
Moktassi, A,
Menezes, R,
Jaskolka, J,
Bleakney, R,
Utility of Time-resolved Contrast-enhanced Magnetic Resonance Angiography in Evaluation of Peripheral Vascular Malformations. Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL.
http://archive.rsna.org/2010/9008278.html