Isabelle Huynh-Charlier MD, Presenter: Nothing to Disclose

Eric Savier MD, Abstract Co-Author: Nothing to Disclose

Fleur Poisot, Abstract Co-Author: Nothing to Disclose

Philippe Charlier MD, Abstract Co-Author: Nothing to Disclose

Philippe A. Grenier MD, Abstract Co-Author: Nothing to Disclose

Olivier Lucidarme MD, Abstract Co-Author: Nothing to Disclose

To review the epidemiology and pathophysiology of HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets). To discuss and illustrate the range of liver complications in HELLP syndrome. To explain the role of imaging in the management of HELLP syndrome.  

Epidemiology and pathophysiology of HELLP syndrome. Liver imaging features in HELLP syndrome (US, CT, arteriography), including hepatomegaly, hepatic perfusion alteration, fatty change of the liver, hepatic necrosis, subcapsular haematoma, ascites and hemoperitoneum. Role of imaging in the management of HELLP syndrome.  

Liver involvement occurs by intravascular fibrin deposits with associated sinusoidal congestion, causing liver necrosis, intraparenchymal or subcapsular haemorrhage, and capsular rupture with vital hemoperitoneum. Detection of liver haemorrhage and study of its extent are crucial to decide treatment: arterial embolization, surgery, transplantation. Arterial embolization should be contested or careful if low or inverse flow is observed in portal vein, to avoid liver necrosis fatal aggravation.

Huynh-Charlier, I, Savier, E, Poisot, F, Charlier, P, Grenier, P, Lucidarme, O, Liver Imaging of HELLP Syndrome.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9008040.html