Manabu Nakata MD, Presenter: Nothing to Disclose

Toshinori Aihara MD, Abstract Co-Author: Nothing to Disclose

Kenichi Utano MD, Abstract Co-Author: Nothing to Disclose

Yuko Otake, Abstract Co-Author: Nothing to Disclose

Waka Nakata MD, Abstract Co-Author: Nothing to Disclose

Hideharu Sugimoto MD, Abstract Co-Author: Nothing to Disclose

To assess the usefulness of liver and spleen volumetry as evaluation of clinical effectiveness of percutaneous transluminal angioplasty for portal venous stenosis complicating pediatric liver transplantation.

A total of 14 cases (5 males, 9 females; mean age 4.4 years) performed percutaneous portal venous balloon angioplasty from July 2007 to July 2009 after pediatric liver transplantation were examined retrospectively. The volumes of the liver (LV) and spleen (SV) were measured by computed tomography (CT) pre- and postoperatively. Spleen volume-to-standard spleen volume ratio (SV/SSV) and LV/SV were calculated in all the cases. Statistical analyses of comparison between pre- and postoperative data and group comparison between each datum of effective and ineffective balloon dilatation groups were performed. Increased rates of LV, SV, SV/SSV, and LV/SV after angioplasties were compared between two groups.

Initial angioplasty achieved clinical success rate of 71% (10 of 14). LV (427.8 ± 172.5 cm3, 479.6 ± 180.2 cm3 for pre-and postoperative values, respectively), SV/SSV (2.67 ± 0.95, 2.25 ± 1.04), and LV/SV (2.57 ± 0.81, 3.15 ± 1.11) had statistical difference between pre-and postoperative data. SV (188.9 ± 97.7 cm3, 176.3 ± 89.8 cm3) had no significant difference. Only in effective group (n=10), LV and LV/SV were significantly increased and SV and SV/SSV were significantly decreased after angioplasty. Increased rate of LV/SSV (1.38 ± 0.17) in effective group was significantly higher than that (0.94 ± 0.28) in ineffective group.

Liver was enlarged and splenomegaly was improved after the balloon dilatation. Our findings suggest that increased rate of LV/SV was highly sensitive to the effect of balloon angioplasty.

CT volumetry offers the potential to provide information about hemodynamic change of portal system after angioplasty, in addition to the morphologic change of the portal vein.

Nakata, M, Aihara, T, Utano, K, Otake, Y, Nakata, W, Sugimoto, H, Liver and Spleen Volumetry as Assessment of Therapeutic Efficacy of Percutaneous Balloon Angioplasty for Portal Venous Stenosis in Pediatric Living Donor Liver Transplant Recipients.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9007016.html