Kristina Elizabeth Hoque PhD, Presenter: Nothing to Disclose

Alexander Lerner MD, Abstract Co-Author: Nothing to Disclose

Jerry Tsu-Yuen Loo BS, Abstract Co-Author: Nothing to Disclose

David A. Stempel MD, MBA, Abstract Co-Author: Nothing to Disclose

Mark S. Shiroishi MD, Abstract Co-Author: Nothing to Disclose

John L. Go MD, Abstract Co-Author: Nothing to Disclose

Monique Annette Mogensen MD, Abstract Co-Author: Research Consultant, Oraya Therapeutics, Inc

Paul E. Kim MD, Abstract Co-Author: Nothing to Disclose

Chi-Shing Zee MD, Abstract Co-Author: Nothing to Disclose

Eu-Meng Law MBBS, Abstract Co-Author: Nothing to Disclose

1. Review anatomy of the intracranial Trigeminal nerve, Gasserian ganglion, and Meckel’s cave and optimal imaging parameters for MRI of this region. 2. Review the differential diagnosis of lesions involving the Meckel’s cave. 3. Present and discuss imaging features and clinical significance of pathology in this region.  

Anatomy •Meckel’s cave and porus trigeminus, Cavernous sinus •Trigeminal nerve and ganglion, V1, V2, V3 and skull base  Optimal imaging techniques Pictorial review of pathology Diseases arising in trigeminal nerve and dura: •Trigeminal nerve schwannoma, Trigeminal neurofibroma, Trigeminal neuritis •Meningioma Diseases of the skull base: •Skull base metastasis •Chondrosarcoma Diseases in subarachnoid space •Lymphoma, Meningitis, Metastatic disease •Petrous apex cephalocele  

Knowledge of Trigeminal nerve and Meckel’s cave anatomy on MRI and CT is instrumental in recognizing and understanding the pathology involving this region. MR cisternography sequences optimally visualize these structures. In addition to meningioma and trigeminal nerve schwannoma, many pathologic processes involving subarachnoid space, skull base, cavernous sinus and head and neck can extend into Meckel’s cave due to its strategic position at the central skull base.

Hoque, K, Lerner, A, Loo, J, Stempel, D, Shiroishi, M, Go, J, Mogensen, M, Kim, P, Zee, C, Law, E, Meckel’s Cave and Gasserian Ganglion Disease: Pictorial Review of CT and MR Imaging Anatomy and Pathology.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9006486.html