Ji Hye Min, Presenter: Nothing to Disclose

Chan Kyo Kim MD, Abstract Co-Author: Nothing to Disclose

Eun Ju Kim BA, Abstract Co-Author: Nothing to Disclose

Byung Kwan Park MD, Abstract Co-Author: Nothing to Disclose

Bohyun Kim MD, Abstract Co-Author: Nothing to Disclose

To prospectively investigate the feasibility of using blood oxygen level-dependent (BOLD) magnetic resonance (MR) imaging at 3T in differentiating the various renal lesions.

70 patients (mean age, 54.1 years; range, 22-80 years) were evaluated with kidney MR imaging including BOLD MR imaging at 3T (Philips Achieva). BOLD MR imaging was performed using a multiple fast field echo (mFFE) sequence to acquire 20 T2*-weighted images within a single breath-hold. With a dedicated software (PRIDE V4.2), color R2* (1/sec) maps were generated and R2* values were calculated by the placement of regions of interest in the various renal lesions, based on the anatomical details of T2-weighted or dynamic contrast-enhanced images. The mean R2* values of solid and benign cystic lesions were compared and moreover, the results of the subgroups (i.e., renal cell carcinomas (RCCs), angiomyolipomas (AMLs), hemorrhagic cysts and simple cysts) were analyzed. Follow-up imaging and histopathologic analysis were used as the reference standards. Statistical analysis was performed by using Mann-Whitney and Kruskal-Wallis test.

96 renal lesions in 70 patients were evaluated: RCCs (n= 29), AMLs (n= 10), hemorrhagic cysts (n= 16), simple cysts (n= 38), urothelial cancer (n=1), lymphoma (n=1) and oncocytoma (n=1). The R2* values of 52 solid lesions (30.7 ± 20.6) were significantly higher than those of 44 benign cystic lesions (4.3 ± 4.5) (P< 0.001). The R2* values of RCCs, AMLs, hemorrhagic cysts and simple cysts were 24.1 ± 13.5, 50.1 ± 25.8, 10.2 ± 3.6 and 1.8 ± 1.7, respectively and there was a significant difference (P< 0.001).

BOLD MR imaging at 3T apprears to be a useful technique for differentiating the various renal lesions.

As an effective supplement of the routine MR protocol, BOLD MR imaging can be used to differentiate the various renal lesions.

Min, J, Kim, C, Kim, E, Park, B, Kim, B, Assessment of Renal Lesions with Blood Oxygen Level-dependent MR Imaging at 3 T: Preliminary Experience.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9004354.html