Koya Nakatani MD, Presenter: Nothing to Disclose

Yuji Nakamoto MD, PhD, Abstract Co-Author: Nothing to Disclose

Kanae Kawai Miyake MD, Abstract Co-Author: Nothing to Disclose

Kensuke Kurihara, Abstract Co-Author: Nothing to Disclose

Kaori Togashi MD, Abstract Co-Author: Nothing to Disclose

1. To understand the concept of IgG4-associated systemic disease. 2. To discuss the clinical role of FDG PET/CT for patients with IgG4-associated diseases.

1.An overview of IgG4-associated systemic disease : Autoimmune pancreatitis and IgG4 / Mikulicz disease and Küttner tumor as IgG4-associated diseases / Various multi-organ manifestations with IgG4-positive plasmacytic infiltration / IgG4-associated systemic disease as an integrated entity 2.The role of FDG PET/CT : To help the diagnosis / To recognize the distribution of activated lesions / Monitoring response to therapy / Our proposal of how to make use of FDG PET/CT

Autoimmune pancreatitis and Mikulicz disease often exist with similar multi-organ manifestations characterized by IgG4-positive plasma cell infiltration. Thus, together with various lymphoplasmacytic sclerosing diseases, an integrated clinicopathological entity, IgG4-associated systemic disease, is being advocated. FDG PET/CT would be useful to help the diagnosis with minimally invasive biopsy, to recognize activated lesions to find out critical disorders, and to monitor response to therapy.

Nakatani, K, Nakamoto, Y, Miyake, K, Kurihara, K, Togashi, K, IgG4-Associated Systemic Disease: How to Make Efficient Use of FDG PET/CT.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9003334.html