1. To present the imaging findings of copper deficiency myeloneuropathy as seen with conventional MRI of the cervical and thoracic spine in two patients.
2. To review the common differential diagnostic considerations.
3. To briefly discuss the neurologic manifestations, pathophysiology and treatment of copper deficiency myeloneuropathy.
Neurologic manifestations and pathophysiology of Copper deficiency myeloneuropathy
Review of imaging findings – Conventional MRI
Sample cases and mimics
Discussion of the common differential diagnostic considerations
Though indistinguishable from subacute combined degeneration of the cord secondary to B12 vitamin deficiency by imaging alone, Copper deficiency myeloneuropathy is a readily treatable and commonly overlooked cause of dorsal column T2 hyperintensity.
Bricker, A,
Jones, S,
Copper Deficiency Myeloneuropathy: A Commonly Overlooked Cause of Dorsal Column T2 Hyperintensity. Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL.
http://archive.rsna.org/2010/9002103.html
