Luke Ienari Sonoda MBBCh, PhD, Presenter: Nothing to Disclose

Mohamed Halim MRCP, Abstract Co-Author: Nothing to Disclose

Kottekkattu K. Balan, Abstract Co-Author: Nothing to Disclose

The importance of monitoring renal function in patients undergoing cystectomy and urinary diversion has been well documented. The aim of this study was to examine the usefulness of pre-operative 99mTc-MAG3 and 51Cr-EDTA GFR for predicting renal function in patients following cystectomy and urinary diversion for cancer.

A retrospective electronic data analysis of 57 patients who underwent cystectomy with ileal conduit urinary diversion for cancer during a 7-year-period was performed. Results of pre and post-operative MAG3, GFR, serum urea and creatinine were obtained and statistically analysed. The patients were divided into stable and deteriorating groups based on their renal function post-operatively for up to 4 years.

There was no statistically significant difference in renal function assessed by MAG3 and GFR between pre-operative and immediate-post-operative studies. Similarly, there was no significant difference in pre-operative MAG3 and GFR results between patients with stable and deteriorating renal function. A single pre-operative or immediate-post-operative MAG3 scan was unable to predict long-term renal function.

Our results confirm the usefulness of 99mTc-MAG3 and 51Cr-EDTA-GFR examinations in monitoring renal function following cystectomy and urinary diversion for cancer. The findings however do not justify the need to do a pre-operative MAG3 or GFR since either seem unable to predict post-operative renal outcome.

Routine pre and immediate-post-operative MAG3 in patients undergoing cystectomy and urinary diversion for bladder cancer do not appear to have any predictive value for surgical outcome.

Sonoda, L, Halim, M, Balan, K, Predictive Value of Preoperative 99mTc-MAG3 and 51Cr-EDTA-GFR on Postsurgical Outcome of Cystectomy and Urinary Diversion for Bladder Cancer.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9002088.html