Zhaoping Cheng MD, MS, Abstract Co-Author: Nothing to Disclose

Yanhua Duan, Abstract Co-Author: Nothing to Disclose

Dawei Wu MD, Abstract Co-Author: Nothing to Disclose

Lebin Wu MD, Abstract Co-Author: Nothing to Disclose

Ximing Wang PhD, Presenter: Nothing to Disclose

This study was designed to compare the results of low-dose prospective ECG-triggering Dual-source CT angiography (DSCTA) with X-ray coronary angiography (XCA) in infants and children with Kawasaki Disease (KD).

This study was local ethics board approved; written informed consent was obtained from all patients. Sixteen children (male 9; mean age: 15 months, range: 6 months to 5 years; mean heart rate: 106 bmp, range: 88-121 bmp) underwent low-dose prospective ECG-triggering DSCTA with free breathing. All patients underwent XCA within a week. The maximal diameter and length of the aneurysm were recorded. Radiation dose values were calculated.  

In eleven patients, aneurysms of the coronary arteries were identified, while coronary ectasia alone was present in the remaining five patients. DSCTA and XCA diagnosis of coronary artery aneurysm agreed completely. Maximal aneurysm diameter and length and ectasia diameter by DSCTA and XCA were similar. No stenotic lesion was identified by either technique. The mean effective dose of the protocol was 0.34 ± 0.06 mSv.

Prospective ECG-triggering DSCTA with very low effective radiation dose allows the accurate diagnosis of coronary artery lesions in infants and children with KD compared with XCA.

Low-dose prospective ECG-triggering DSCT angiography is an excellent and non-invasive examination method for infants and children with Kawasaki Disease.

Cheng, Z, Duan, Y, Wu, D, Wu, L, Wang, X, Diagnostic Performance of Low-dose Prospective ECG-triggering Dual-source CT Angiography Compared with Conventional X-Ray Angiography in Kawasaki Disease.  Radiological Society of North America 2010 Scientific Assembly and Annual Meeting, November 28 - December 3, 2010 ,Chicago IL. http://archive.rsna.org/2010/9001924.html