AIM provides a standard for medical imaging annotation and markups for images used in the research space, and in particular, the image based cancer clinical trial. It is notable that there is no existing standard for radiology annotation and markup. The caBIG® program is working with almost every standards body such as DICOM to elicit consensus regarding using AIM as the accepted standard for radiology annotation and markup, and is positioned to extend AIM to digital pathology.

Annotations and Imaging Markup Developer (AIM).  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8503046.html