RSNA 2009 

Abstract Archives of the RSNA, 2009


SSK16-07

Endometrial Cancers: Correlation of Standardized Uptake Values of Integrated FDG PET/CT and Histopathologic Findings

Scientific Papers

Presented on December 2, 2009
Presented as part of SSK16: ISP: Nuclear Medicine (Clinical Utility of Quantitative Imaging)

Participants

Kimihiko Sato MD, Presenter: Nothing to Disclose
Takayuki Masui MD, Abstract Co-Author: Nothing to Disclose
Motoyuki Katayama MD, Abstract Co-Author: Nothing to Disclose
Hiroki Ikuma MD, Abstract Co-Author: Nothing to Disclose
Hidekazu Seo MD, Abstract Co-Author: Nothing to Disclose

PURPOSE

To clarify the relationship between standardized uptake values(SUV) of integrated FDG PET/CT and histopathologic findings in patients with endometrial cancers.

METHOD AND MATERIALS

 Thirty consecutive women (mean age, 54.9 years) with endometrial cancer who underwent radical hysterectomy and pelvic dissection were investigated for maximum SUV of FDG PET/CT in correlation with tumor size, tumor depth, histopathologic grade and associated histopathologic inflammation.

RESULTS

Maximum SUV of FDG PET/CT was positively correlated with tumor size (correlation coefficient, 0.87; P < .0001). The group of endometrial cancer associated with histopathologic active inflammation had significant higher maximum SUV than the group of endometrial cancer associated with histopathologic inactive inflammation. Neither tumor depth nor histopathologic grade correlated with maximum SUV.

CONCLUSION

Standardized uptake values for endometrial cancers correlated with tumor size and with the degree of histopathologic inflammation.

CLINICAL RELEVANCE/APPLICATION

 The correlation between FDG uptake and tumor grade can not demonstrate for endometrial cancers.

Cite This Abstract

Sato, K, Masui, T, Katayama, M, Ikuma, H, Seo, H, Endometrial Cancers: Correlation of Standardized Uptake Values of Integrated FDG PET/CT and Histopathologic Findings.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8015579.html