Chae Yeon Lyou MD, Presenter: Nothing to Disclose

Sun Mi Kim MD, Abstract Co-Author: Nothing to Disclose

Mijung Jang, Abstract Co-Author: Nothing to Disclose

To retrospectively compare magnectic resonance imaging (MRI) findings of screening-detected and symptomatic ductal carcinoma in situ (DCIS)

Of 197 patients who were diagnosed to DCIS on final histology in our institution between September 2003 and March 2009, 45 screening-detected and 27 symptomatic lesions from 67 patients (mean age 49, range 25-76 years) who were confirmed with 14G core needle biopsy and underwent preoperative breast MRI were enrolled. Three breast imaging radiologists reviewed MRI, ultrasound and mammography findings by consensus according to Breast Imaging Reporting and Data System (BI-RADS). Medical records and pathologic reports were also reviewed. Statistically, we compared the differences of MRI findings between two groups (screening-detected and symptomatic) by Chi-square test. Using independent T-test, we calculated the mean size of the lesions in each groups.

Screening-detected cases presented as 21 masses and 25 nonmass-like enhancement (NMLE) and symptomatic cases as 9 masses and 17 NMLE (Chi-square = 0.44, p = 0.51). Other morphologic findings such as shape, margin, homogeneity, or internal enhancement patterns had also no statistical difference (Chi-square = 4.90, 1.20, 4.30, and 1.28; p = 0.43, 0.85, 0.51, and 0.73, respectively). In delayed phase, screening-detected cases showed 3 no enhancement, 14 persistent, 27 plateau, and 1 washout patterns. Symptomatic cases showed 2 no enhancement, 9 persistent, 14 plateau, and 2 washout patterns. There is no significant difference in terms of kinetic characteristic. Mean sizes of enhancing lesions were 23.49cm (SEM = 2.30) in screening-detected group and 29.19cm (SEM = 3.35) in symptomatic group. No significant size difference was between two groups (p = 0.17). Ultrasound, mammographic finding and histologic grade showed similar results as MRI (Chi-square = 3.35, 5.69 and 0.24; p = 0.19, 0.34 and 0.89, respectively).

Most common MRI findings of DICS according to BI-RADS was nonmass-like enhancing lesion with plateau kinetic characteristic and showed no significant difference between screening-detected and symptomatic DCIS.

Screening-detected DCIS shows similar MRI finding with symptomatic DCIS.

Lyou, C, Kim, S, Jang, M, Magnetic Resonance Imaging of Ductal Carcinoma in Situ: Is There Any Difference between Screening-detected and Symptomatic Patients?.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8013958.html