Jae Sung Myung MD, Presenter: Nothing to Disclose

Sung Hwan Hong, Abstract Co-Author: Nothing to Disclose

Ja-Young Choi MD, Abstract Co-Author: Nothing to Disclose

Su Jin Kim, Abstract Co-Author: Nothing to Disclose

Joon Woo Lee, Abstract Co-Author: Nothing to Disclose

Jung-Ah Choi MD, Abstract Co-Author: Nothing to Disclose

Heung Sik Kang MD, Abstract Co-Author: Nothing to Disclose

00030490-DMT et al, Abstract Co-Author: Nothing to Disclose

To evaluate the MR imaging features related with local recurrence after surgery of giant cell tumor of bone (GCT) and to determine the most reliable predictor of recurrence

Preoperative MR images of 46 patients with more than 2 year follow-up that was confirmed at surgery from 2000 to 2007 were retrospectively reviewed. Recurrence was found in 15 (32.6%) of 46 patients. On MR images, cortical breakage, subchondral bone extension, perilesional bone marrow edema, surrounding soft tissue enhancement, and cystic change were analyzed. MR imaging features were compared between recurred group and non-recurred group using univariate analysis and then multivariate stepwise logistic regression analysis was performed.

A Pearson's Chi-square test revealed that cortical breakage were more frequently seen in recurred group (n = 9, 60%) than non-recurred group (n = 6, 19%) (p = 0.01). The other MR imaging features was not statistically significant between recurred group and non-recurred group. Multivariate stepwise logistic regression analysis showed that cortical breakage could be the only predictor of recurrence (p = 0.04, OR = 4.73, 1.07 < 95% CI < 20.94).

Cortical breakage among MR imaging features of GCT is the only reliable predictor of recurrence

Recognition of MR imaging predictors of recurrence of GCT can bring awareness of dealing with a tumor more vulnerable to recurrence to radiologist and surgeon

Myung, J, Hong, S, Choi, J, Kim, S, Lee, J, Choi, J, Kang, H, et al, 0, MR Imaging of Giant Cell Tumor of Bone: Prediction of Recurrence.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8013885.html