Young Kag Bahn RT, Presenter: Nothing to Disclose

Hoon-Hee Park MS, RT, Abstract Co-Author: Nothing to Disclose

Hyuk Nam-Koong RT, Abstract Co-Author: Nothing to Disclose

Sang Kyu Kim, Abstract Co-Author: Nothing to Disclose

Chang Ho Lee MS, Abstract Co-Author: Nothing to Disclose

The menstrual cycle of normal premenopausal patients was divide into menstrual flow phase, proliferative phase, ovulatory phase, secretory phase. The aim of this study was to ovarian and endometrial 18F-FDG uptake during the menstrual cycle in normal premenopausal patients.

We identified 200 incidental 18F-FDG uptake in the ovary. The patient fasted at least 6 hours before receiving an intravenous injection of 370-592 MBq (10-16mCi) of 18F-FDG. Scanning from the base of the skull though the mid thigh was performed using the Discovery STe PET/CT system (GE Healthcare, Milwaukee, WI, USA). Ovarian and endometrial 18F-FDG uptake (expressed as standardized uptake value) was measured on PET/CT image.

Two peaks of increased endometrial 18F-FDG uptake were identified during the menstrual cycle. The SUVavg and SUVmax was 2.89±1.04 g/ml and 3.17±1.59 g/ml in menstruating patients, 2.4±0.88 g/ml and 2.98±1.14 g/ml in proliferative phase patients, 3.59±1.76 g/ml and 3.17±1.67 g/ml in ovulatory phase patients, 2.58±1.39 g/ml and 3.1±1.8 g/ml in secretory phase patients.

Increased ovarian and endometrial 18F-FDG uptake could be found the time of menstrual flow and ovulatory phase of menstrual cycle. Increased uptake in endometrial adjacent to a cervical tumor does not necessarily reflect endometrial tumor invasion. Since increased uptake was dependent on the menstrual cycle, it can be avoided by scheduling PET/CT just after menstruation. Non-menstrual-related endometrial uptake may be instrumental in establishing a diagnosis in a premenopaual patients.

 

Bahn, Y, Park, H, Nam-Koong, H, Kim, S, Lee, C, Ovarian and Endometrial 18F-FDG Uptake during the Menstrual Cycle in Normal Premenopausal Patients: Evaluation by PET/CT.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8010171.html