Kenji Suzuki PhD, Presenter: Research grant, Riverain Medical Research grant, Hitachi, Ltd License agreement, Riverain Medical License agreement, MEDIAN Technologies Research Consultant, Riverain Medical Royalty distribution as research fund, Riverain Medical Royalty distribution as research fund, MEDIAN Technologies Royalty distribution as research fund, Hologic, Inc Royalty distribution as research fund, General Electric Company Royalty distribution as research fund, Toshiba Corporation Royalty distribution as research fund, Mitsubishi Corporation

Masatoshi Hori MD, Abstract Co-Author: Nothing to Disclose

Elizabeth Gerard McFarland MD, Abstract Co-Author: Medical Advisory Board, Medicsight, Inc

Arnold Carl Friedman MD, Abstract Co-Author: Medical Advisory Board, Calgary Scientific, Inc Co-owner, CTC @ Home Medical Advisory Board, Medicexchange PLC

Don C. Rockey MD, Abstract Co-Author: Nothing to Disclose

Abraham H. Dachman MD, Abstract Co-Author: Consultant, iCAD, Inc Consultant, General Electric Company

1) To learn two major sources of false negatives in CT colonography (CTC) in a multicenter clinical trial. 2) To experience interactively a computer-aided detection (CADe) system for polyps in CTC. 3) To learn the potential usefulness and pitfalls of the system in detection of polyps “missed” by reporting radiologists in the original trial.

A. Sources of false-negative interpretations in a multicenter clinical trial B. Performance of our CADe system on “missed” polyps including flat lesions C. Beneficial and detrimental effects of CADe on radiologists’ performance D. Pitfalls with CADe: Relationships among false negatives and false positives by a computer and radiologists E. Case review from observer performance study without and with CADe  

Our observer performance study demonstrated that the average sensitivity of radiologists in detection of “difficult’ polyps was improved from 67% to 72% with CADe at a statistically significant level (P<<.05). This exhibit reviews a. Detection of “difficult’ polyps by our CADe system b. Performance of radiologists without and with CADe c. Pitfalls for radiologists in polyp detection with CADe  

Suzuki, K, Hori, M, McFarland, E, Friedman, A, Rockey, D, Dachman, A, Can CAD Help Improve the Performance of Radiologists in Detection of “Difficult” Polyps in CT Colonography?.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8008355.html