Maria Arraiza MD, Presenter: Nothing to Disclose

Javier Arias MD, Abstract Co-Author: Nothing to Disclose

Beatriz Zudaire MD, Abstract Co-Author: Nothing to Disclose

Stefano Mastrobuoni, Abstract Co-Author: Nothing to Disclose

Gregorio Rabago, Abstract Co-Author: Nothing to Disclose

Gorka Bastarrika MD, Abstract Co-Author: Nothing to Disclose

To assess accuracy of global left ventricular (LV) function and mass quantification with ten and twenty multiphase cardiac dual-source CT (DSCT) reconstructions as compared with MRI in heart transplant recipients.

Nineteen heart transplant recipients (17 male, mean age 61.9±14.2 years, mean transplant time 121.05±71.98 months) who underwent cardiac DSCT and MRI examinations were prospectively included. For the assessment of LV parameters cardiac DSCT reconstructions obtained at 5% (twenty phases) and 10% (ten phases) intervals of the cardiac cycle with MRI double-oblique short-axis images were compared. In all individuals ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and myocardial mass were determined using commercially available semiautomated segmentation analysis software tool for DSCT data and conventional manual contour tracing for MR studies.

Quantification of LV parameters using different reconstruction intervals at DSCT led to non-significant differences (p>0.05). When compared to MRI significant overestimation of LV volumes and mass was observed with DSCT in both 5% (mean difference EDV: 20.79±29.02 ml; ESV: 14.68±17.34 ml; mass 36.89±14.47 g) and 10% (mean difference EDV: 18.31±28.19 ml; ESV: 11.37±19.45 ml; mass 35.53±15.58 g) reconstruction intervals, whereas not significant differences were observed in EF and SV estimation.

In heart transplant recipients DSCT allows reliable quantification of LV function and mass compared with MRI, even using 10% interval reconstructions.

DSCT allows reliable quantification of LV function and mass compared with MRI in heart transplant recipients even using 10% interval reconstructions.

Arraiza, M, Arias, J, Zudaire, B, Mastrobuoni, S, Rabago, G, Bastarrika, G, Dual-Source CT Quantification of Left Ventricular Function and Mass in Heart Transplant Recipients: Effect of Number of Reconstruction Phases on Measurement Accuracy.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8006031.html