Yumi Yanaga MD, Presenter: Nothing to Disclose

Kazuo Awai MD, Abstract Co-Author: Nothing to Disclose

Takeshi Nakaura MD, Abstract Co-Author: Nothing to Disclose

Daisuke Utsunomiya MD, Abstract Co-Author: Nothing to Disclose

Toshinori Hirai MD, Abstract Co-Author: Nothing to Disclose

Yasuyuki Yamashita MD, Abstract Co-Author: Nothing to Disclose

Seitaro Oda MD, Abstract Co-Author: Nothing to Disclose

00030490-DMT et al, Abstract Co-Author: Nothing to Disclose

To investigate the effect on aortic enhancement of contrast material volumes adjusted for the patients' body surface area (BSA) at computed tomography angiography (CTA).

Using a 64-detector CT scanner, 89 patients (48 men and 41 women; age range 48 -86 years; mean 68.7 years) with confirmed or suspected aortoiliac disease underwent CTA of the whole aorta. The patients were divided into a body weight (BW, n=45) and a BSA (n=44) group. The contrast dose was 360 mgI/kg BW in the BW- and 12,753 mgI/m2 BSA in the BSA group. As the average BW of Japanese individuals is approximately 60 kg, the contrast dose in the 2 protocols was identical in patients weighing 60 kg. We compared aortic enhancement achieved with the 2 protocols by the two-tailed t-test and we used the generalized linear model (GLM) to analyze the effect of age, sex, and BW on aortic enhancement in each protocol group.

Mean aortic enhancement in the BW- and the BSA groups was 324.2 and 311.7 HU, respectively; the difference was not significant (p = 0.26). In the BW group, the BW had a statistically significant effect on aortic enhancement (p < 0.01), the age or sex did not (p = 0.08 and 0.07, respectively). In the BSA group, the age, sex, BW, and BW x sex had no statistically significant effect on aortic enhancement (p = 0.33, 023, 0.10 and 0.16, respectively).

Under the BSA protocol, aortic enhancement tended to be consistent and adequate irrespective of the BW.

A contrast injection protocol with iodine dose adjusted for the body surface area can estimate optimal iodine doses to each patient while maintaining adequate aortic enhancement at CT angiography.

Yanaga, Y, Awai, K, Nakaura, T, Utsunomiya, D, Hirai, T, Yamashita, Y, Oda, S, et al, 0, Contrast Material Injection Protocol with the Dose Adjusted to the Body Surface Area for Thoracoabdominal Multidetector CT Angiography: Initial Experience.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8003441.html