Kefeng Zhou, Presenter: Nothing to Disclose

Bin Zhu, Abstract Co-Author: Nothing to Disclose

Junkun Chen, Abstract Co-Author: Nothing to Disclose

To evaluate the value of multi-slice spiral CT perfusion imaging in differential diagnosis between benign and malignant pulmonary nodules

64 patients who had the pulmonary nodules with the pathological results underwent 16-helical CT perfusion imaging, The blood flow(BF), blood volume(BV) , mean transit time(MTT) , permeability surface(PS) and time-density curve (TDC) were analyzed by CT perfusion 3-body tumor software

the difference of BV and PS were statistically significant among malignant、 inflammatory and benign nodules, PS parameter in pulmonary malignant nodules was higher than those in benign and inflammatory nodules. Make BV≤4.00ml/100g as the diagnostic criteria of benign nodules, sensitivity 80%, specificity 85.2%, positive predictive value 50% and negative predictive value 95.8%. make PS≥7ml.100g -1.ml-1 as the liminal value of malignant nodules, sensitivity 82.4%, specificity 82.4%, positive predictive value 93.3% and negative predictive value 82.4%. The shapes of TDC were also different among the malignant , inflammatory , and benign nodules.

CT Perfusion imaging provides the quantitative information about blood flow patterns of pulmonary nodules and it has the great value in differential diagnosis between benign and malignant nodules.

CT perfusion in pulmonary nodules give us the exact information of the blood flow to help to decide the character of the nodules

Zhou, K, Zhu, B, Chen, J, The Diagnosis and Differential Diagnosis with Multislice Spiral CT Perfusion Imaging in Pulmonary Nodules.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8001297.html