Kefeng Zhou, Presenter: Nothing to Disclose

Junkun Chen, Abstract Co-Author: Nothing to Disclose

Bin Zhu, Abstract Co-Author: Nothing to Disclose

To investigate a new technique for measuring glomerular filtration rate in a single kidney by multi-slice spiral CT and evaluate the accuracy

20 patients were both underwent abdominal multi-phasic enhancement CT scan and SPECT to measure the GFR in a single kidney. Using the known Patlak equation, the GFR in a single kidney was calculated in CT scan and the exact information of GFR was gained by performing renal SPECT with Tc99m-TDPA. GFR of the two groups were analysed by linear regression analysis

Linear regression analysis show that the two group GFR had very well associativity . the correlation coefficient of whole kidney and divided one is 0.896and 0.956, with a line of regression GFR（CT）=21.724+0.742×GFR(ECT)，n=20(the whole kidney); GFR（CT）=7.040+0.846 ×GFR(ECT)，n=40(the divided kidney),they have no statistical significance in pair t test（P>0.05）

The multi-phasic 16-slice helical CT can evaluate not only the anatomy but also the function of the kidney, and CT-clearance was well correlated with ECT-clearance. To some extent, This technique can replace SPECT to measure GFR in single kidney in patients

we could know not only the anatomical information such as location and character of the lesion through CT scan, but also the functional information of GFR

Zhou, K, Chen, J, Zhu, B, Glomerular Filtration Rate in a Single Kidney Measured by Multi-slice Helical CT.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8001293.html