Hao Sun MD, Presenter: Nothing to Disclose

Huadan Xue MD, Abstract Co-Author: Nothing to Disclose

Wei Liu, Abstract Co-Author: Nothing to Disclose

Xuan Wang MD, Abstract Co-Author: Nothing to Disclose

Yu Chen, Abstract Co-Author: Nothing to Disclose

Zheng Yu Jin MD, Abstract Co-Author: Nothing to Disclose

To investigate the perfusion characteristics of renal mass parenchyma and normal renal cortex, and to compare the volume of normal kidney and serum creatinine (SCr) before and after arterial embolization on 64-slice spiral computed tomography.

Totally 21 patients with renal tumor were enrolled. Sixty-four slice spiral CT was used for renal perfusion scan that began with a contrast bolus injection of 50 ml (370 mgI/ml) at a rate of 5 ml/s before and after patients having tumor arterial embolization. Perfusion characteristics, including blood flow (BF), blood volume (BV) and permeability (PM) of renal mass parenchyma and renal cortex in normal kidneys were calculated from Siemens Body PCT (VB20B) software. The volume of normal kidneys was measured from Siemens Volume (VB20B) software. The values of SCr in all patients were documented. Before and after embolization, the perfusion characteristics, the volume of normal kidneys and the level of SCr were compared.

Renal clear cell carcinoma(RCCC) was pathologically confirmed in all patients. Before and after having supply blood arterial embolization of renal tumor, perfusion characteristics of tumor parenchyma significantly decreased, perfusion characteristics of renal cortex in normal kidney significantly increased and the volume of normal kidneys significantly enlarged (P<0.01), while there were no significant differences (P>0.05) in the values of SCr in all patients (P>0.05).

The perfusion characteristics and volume of kidney may reflect the effects of renal arterial embolization on renal function. Perfusion imaging with multi-slice spiral CT is potentially useful in the evaluation of renal pathophysiological characteristics.

As a kind of dynamic functional CT imaging, perfusion imaging with MSCT has potential clinical application values in evaluation of renal function and treatment effects.

Sun, H, Xue, H, Liu, W, Wang, X, Chen, Y, Jin, Z, The Perfusion Characteristics of Renal Tumor and Volume of Normal Kidney before and after Arterial Embolization with 64-Slice Spiral Computed Tomography.  Radiological Society of North America 2009 Scientific Assembly and Annual Meeting, November 29 - December 4, 2009 ,Chicago IL. http://archive.rsna.org/2009/8000416.html