Tomohiro Namimoto MD, Presenter: Nothing to Disclose

Kazuo Awai MD, Abstract Co-Author: Nothing to Disclose

Tetsuo Saito, Abstract Co-Author: Nothing to Disclose

Takeshi Nakaura MD, Abstract Co-Author: Nothing to Disclose

Masanori Imuta MD, Abstract Co-Author: Nothing to Disclose

Yasuyuki Yamashita MD, Abstract Co-Author: Nothing to Disclose

Yumi Yanaga MD, Abstract Co-Author: Nothing to Disclose

et al, Abstract Co-Author: Nothing to Disclose

The purpose of this study was to measure the apparent diffusion coeffcient (ADC) values calculated from diffusion-weighted MR imaging (DWI) of malignant masses with solid components in the ovary and compare them with those of benign masses, and to test whether ADC could differentiate between malignant and benign masses in the ovary.

DWI was performed in 25 patients with 25 ovarian masses with solid components (6 clear cell-, 5 endometrioid-, and 3 poorly differentiated adenocarcinomas, 4 serous cystadenocarcinomas, 2 metastases, 2 fibromas, 2 struma ovarii, and 1 malignant lymphoma). The ADC was measured at a 3T MR scanner with b-factors of 0, 800, or 1000 s/mm² using single-shot echo-planar DWI and a parallel imaging technique. The areas with the highest signal intensity on DWI (b=800 or 1000 s/mm²) and the mean ADC values within the solid ovarian components were evaluated.

The mean ADC value of malignant ovarian masses, benign masses, and normal ovary were 0.97 ± 0.20, 1.81 ± 0.04, and 1.68 ± 0.32 ×10¯³ mm²/s, respectively. The ADC of malignant masses was significantly lower than of benign masses and normal ovary (Tukey’s multiple comparison, p < 0.01).

Our preliminary results indicated that the ADC value might be useful for the differential diagnosis of ovarian masses with solid components.

ADC values may help to differentiate malignant ovarian masses with solid components from benign ovarian masses.

Namimoto, T, Awai, K, Saito, T, Nakaura, T, Imuta, M, Yamashita, Y, Yanaga, Y, et al, , Diffusion-weighted Echo-planar 3 T MRI and ADC Mapping in the Differential Diagnosis of Ovarian Masses with Solid Components: Usefulness for Detecting Malignant Tumors.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6019986.html