Luba Frank MD, Presenter: Nothing to Disclose

Smita Patel MBBS, Abstract Co-Author: Nothing to Disclose

Naama R. Bogot MD, Abstract Co-Author: Research Consultant, Siemens AG

Ella A. Kazerooni MD, Abstract Co-Author: Consultant, General Electric Company Consultant, Vital Images, Inc Research funded, General Electric Company

1. To review pathophysiology and clinical implications of  noncalcified plaque. 2. To review the CT appearance of eccentric vs. concentric plaque and focal vs. diffuse non-calcified plaque (assessment of degree of stenosis), correlation with conventional angiography. 3. To review the CT appearance of positive and negative remodeling

Pathophysiology and clinical implications of the non calcified plaque Imaging technique Assessment of non calcified plaque using MDCT64 Coronary Angiography Distribution, degree of stenosis and correlation with conventional angiography Positive and negative remodeling Future research  

Non-calcified plaque that demonstrates positive remodeling and fatty attenuation is thought to be potentially vulnerable.  An area of future research is patient outcome in the presence of non-calcified plaque causing varying degree of stenosis and demonstrating positive remodeling. Another important area of future research is plaque burden quantification which could help risk stratification and evaluation of plaque stability or regression following treatment with statins.

Frank, L, Patel, S, Bogot, N, Kazerooni, E, Noncalcified Coronary Artery Plaque: From Pathophysiology to Imaging.  Radiological Society of North America 2008 Scientific Assembly and Annual Meeting, February 18 - February 20, 2008 ,Chicago IL. http://archive.rsna.org/2008/6019120.html